The Collaborative International Dictionary of English v.0.48:

Fuddle \Fud"dle\, v. t. [imp. & p. p. Fuddled; p. pr. & vb. n.
   Fuddling.] [Perh. formed as a kind of dim. of full. Cf.
   Fuzzle.]
   To make foolish by drink; to cause to become intoxicated.
   [Colloq.]
   [1913 Webster]

         I am too fuddled to take care to observe your orders.
                                                  --Steele.
   [1913 Webster]

WordNet (r) 3.0 (2006):

fuddled
    adj 1: very drunk [syn: besotted, blind drunk, blotto,
           crocked, cockeyed, fuddled, loaded, pie-eyed,
           pissed, pixilated, plastered, slopped, sloshed,
           smashed, soaked, soused, sozzled, squiffy,
           stiff, tight, wet]

Moby Thesaurus II by Grady Ward, 1.0:

127 Moby Thesaurus words for "fuddled":
   addlebrained, addled, addleheaded, addlepated, afflicted, apish,
   asinine, at a loss, baffled, bamboozled, batty, beat, beclouded,
   befooled, befuddled, beguiled, bent, besotted, boiled, bombed,
   boozy, brainless, buffaloed, buffoonish, canned, cloudy, cockeyed,
   cockeyed drunk, confounded, crazy, credulous, crocked, crocko,
   daffy, daft, dazed, dizzy, doting, dumb, elevated, fatuitous,
   fatuous, flaky, floored, fogged, foggy, fond, fool, foolheaded,
   foolish, fried, fuddlebrained, futile, gaga, goofy, gulled,
   half-seas over, hazy, high, idiotic, illuminated, imbecile,
   in a dilemma, in a fog, in a muddle, in suspense, inane, inept,
   infatuated, insane, kooky, licked, lit, lit up, loaded, loony,
   lubricated, lushy, mad, maudlin, misted, misty, moronic, muddled,
   muddleheaded, muzzy, mystified, nonplussed, nutty, oiled,
   on tenterhooks, organized, perplexed, pickled, pie-eyed, pissed,
   pissy-eyed, plastered, polluted, potted, puzzled, puzzleheaded,
   raddled, sappy, screwy, senseless, sentimental, shellacked, silly,
   skunk-drunk, smashed, soaked, soused, squiffy, stewed, stinko,
   stuck, stumped, stupid, swacked, tanked, thoughtless, thrown,
   tight, wacky, wet, witless