The Collaborative International Dictionary of English v.0.48:

Hurtful \Hurt"ful\, a.
   Tending to impair or damage; injurious; mischievous;
   occasioning loss or injury; as, hurtful words or conduct.

   Syn: Pernicious; harmful; baneful; prejudicial; detrimental;
        disadvantageous; mischievous; injurious; noxious;
        unwholesome; destructive. -- Hurt"ful*ly, adv. --
        Hurt"ful*ness, n.
        [1913 Webster]

WordNet (r) 3.0 (2006):

hurtful
    adj 1: causing hurt; "her hurtful unconsidered words"
    2: harmful to living things; "deleterious chemical additives"
       [syn: deleterious, hurtful, injurious]