1. 
[syn: annoying, bothersome, galling, irritating, nettlesome, pesky, pestering, pestiferous, plaguy, plaguey, teasing, vexatious, vexing]
The Collaborative International Dictionary of English v.0.48:
Bothersome \Both"er*some\, a.
   Vexatious; causing bother; causing trouble or perplexity;
   troublesome.
   [1913 Webster]
WordNet (r) 3.0 (2006):
bothersome
    adj 1: causing irritation or annoyance; "tapping an annoying
           rhythm on his glass with his fork"; "aircraft noise is
           particularly bothersome near the airport"; "found it
           galling to have to ask permission"; "an irritating
           delay"; "nettlesome paperwork"; "a pesky mosquito";
           "swarms of pestering gnats"; "a plaguey newfangled safety
           catch"; "a teasing and persistent thought annoyed him";
           "a vexatious child"; "it is vexing to have to admit you
           are wrong" [syn: annoying, bothersome, galling,
           irritating, nettlesome, pesky, pestering,
           pestiferous, plaguy, plaguey, teasing,
           vexatious, vexing]
Moby Thesaurus II by Grady Ward, 1.0:
48 Moby Thesaurus words for "bothersome":
   aggravating, annoying, backbreaking, besetting, bothering,
   burdensome, chafing, crushing, disquieting, distressful,
   distressing, disturbing, exasperating, fretting, galling, grueling,
   harassing, heavy, hefty, importunate, importune, irking, irksome,
   irritating, onerous, oppressive, painful, pesky, pestering,
   pestiferous, pestilent, pestilential, plaguesome, plaguey,
   plaguing, provoking, teasing, tiresome, tormenting, troublesome,
   troubling, trying, upsetting, vexatious, vexing, wearisome,
   worrisome, worrying