The Collaborative International Dictionary of English v.0.48:

anguished \anguished\ adj. [p. p. from anguish.]
   suffering anguish; experiencing extreme pain, distress, or
   anxiety

   Syn: suffering, tormented
        [WordNet 1.5]

WordNet (r) 3.0 (2006):

anguished
    adj 1: experiencing intense pain especially mental pain; "an
           anguished conscience"; "a small tormented schoolboy"; "a
           tortured witness to another's humiliation" [syn:
           anguished, tormented, tortured]

Moby Thesaurus II by Grady Ward, 1.0:

54 Moby Thesaurus words for "anguished":
   aching, aggrieved, anxious, bleeding, bored, bruised, careworn,
   cheerless, cut, depressed, disgusted, doleful, dolorous,
   dumb with grief, grief-stricken, griefful, grieved, grievous, grim,
   hurt, in grief, injured, joyless, lamentable, lugubrious, mauled,
   mournful, nauseated, nauseous, pained, plaintive, plangent,
   pleasureless, plunged in grief, prey to malaise, repelled,
   revolted, rueful, sad, sickened, sorrowed, sorrowful, sorrowing,
   stung, suffering angst, tearful, uneasy, unfulfilled, ungratified,
   unhappy, unquiet, unsatisfied, woeful, wounded