The Collaborative International Dictionary of English v.0.48:

Physic \Phys"ic\ (f[i^]z"[i^]k), n. [OE. phisike, fisike, OF.
   phisique, F. physique knowledge of nature, physics, L.
   physica, physice, fr. Gr. fysikh`, fr. fysiko`s natural, from
   fy`sis nature, fr. fy`ein to produce, grow, akin to E. be.
   See Be, and cf. Physics, Physique.]
   1. The art of healing diseases; the science of medicine; the
      theory or practice of medicine; -- an archaic term,
      superseded by medicine. [archaic] "A doctor of physik."
      --Chaucer.
      [1913 Webster]

   2. A specific internal application for the cure or relief of
      sickness; a remedy for disease; a medicine.
      [1913 Webster]

   3. Specifically, a medicine that purges; a cathartic.
      [1913 Webster]

   4. A physician. [R.] --Shak.
      [1913 Webster]

   Physic nut (Bot.), a small tropical American euphorbiaceous
      tree (Jatropha Curcas), and its seeds, which are well
      flavored, but contain a drastic oil which renders them
      dangerous if eaten in large quantities.
      [1913 Webster]

The Collaborative International Dictionary of English v.0.48:

Medicine \Med"i*cine\, v. t.
   To give medicine to; to affect as a medicine does; to remedy;
   to cure. "Medicine thee to that sweet sleep." --Shak.
   [1913 Webster]

The Collaborative International Dictionary of English v.0.48:

Medicine \Med"i*cine\, n. [L. medicina (sc. ars), fr. medicinus
   medical, fr. medicus: cf. F. m['e]decine. See Medical.]
   1. The science which relates to the prevention, cure, or
      alleviation of disease.
      [1913 Webster]

   2. Any substance administered in the treatment of disease; a
      remedial agent; a medication; a drug; a pharmaceutical; a
      medicament; a remedy; physic.
      [1913 Webster]

            By medicine, life may be prolonged.   --Shak.
      [1913 Webster]

   3. A philter or love potion. [Obs.] --Shak.
      [1913 Webster]

   4. [F. m['e]decin.] A physician. [Obs.] --Shak.
      [1913 Webster]

   5.
      (a) Among the North American Indians, any object supposed
          to give control over natural or magical forces, to act
          as a protective charm, or to cause healing; also,
          magical power itself; the potency which a charm,
          token, or rite is supposed to exert.
          [Webster 1913 Suppl.]

                The North American Indian boy usually took as
                his medicine the first animal of which he
                dreamed during the long and solitary fast that
                he observed at puberty.           --F. H.
                                                  Giddings.
          [Webster 1913 Suppl.]
      (b) Hence, a similar object or agency among other savages.
          [Webster 1913 Suppl.]

   6. Short for Medicine man.
      [Webster 1913 Suppl.]

   7. Intoxicating liquor; drink. [Slang]
      [Webster 1913 Suppl.]

   Medicine bag, a charm; -- so called among the North
      American Indians, or in works relating to them.

   Medicine man (among the North American Indians), a person
      who professes to cure sickness, drive away evil spirits,
      and regulate the weather by the arts of magic; a shaman.


   Medicine seal, a small gem or paste engraved with reversed
      characters, to serve as a seal. Such seals were used by
      Roman physicians to stamp the names of their medicines.
      [1913 Webster]

WordNet (r) 3.0 (2006):

medicine
    n 1: the branches of medical science that deal with nonsurgical
         techniques [syn: medicine, medical specialty]
    2: (medicine) something that treats or prevents or alleviates
       the symptoms of disease [syn: medicine, medication,
       medicament, medicinal drug]
    3: the learned profession that is mastered by graduate training
       in a medical school and that is devoted to preventing or
       alleviating or curing diseases and injuries; "he studied
       medicine at Harvard" [syn: medicine, practice of
       medicine]
    4: punishment for one's actions; "you have to face the music";
       "take your medicine" [syn: music, medicine]
    v 1: treat medicinally, treat with medicine [syn: medicate,
         medicine]

Moby Thesaurus II by Grady Ward, 1.0:

103 Moby Thesaurus words for "medicine":
   anatomy, anesthesiology, audiology, bacteriology, balm, balsam,
   cardiology, chiropody, corpse reviver, cure, cure-all,
   dental surgery, dentistry, dermatology, diagnostics, drops, drug,
   electuary, elixir, embryology, endocrinology, epidemiology,
   ethical drug, etiology, exodontics, firewater, fluoroscopy,
   generic name, geriatrics, gerontology, healing arts, hematology,
   herbs, hooch, hygiene, immunochemistry, immunology, inhalant,
   internal medicine, likker, lincture, linctus, materia medica,
   medical care, medical treatment, medicament, medication, medicinal,
   medicinal herbs, medicines, mental hygiene, mixture, mycology,
   neurology, neurosurgery, nonprescription drug, nostrum, nutrition,
   obstetrics, officinal, ophthalmology, optometry, orthodontics,
   otolaryngology, otology, panacea, patent medicine, pathology,
   periodontics, pharmaceutical, pharmacon, physic, physical medicine,
   powder, preparation, prescription, prescription drug, proprietary,
   proprietary medicine, proprietary name, psychiatry, psychoanalysis,
   psychology, psychotherapy, radiology, remedy, sauce, semeiology,
   serology, simples, snake medicine, surgery, symptomatology, syrup,
   teratology, therapeusis, therapeutics, theraputant, therapy,
   tiger milk, tisane, treatment, vegetable remedies



The Devil's Dictionary (1881-1906):

MEDICINE, n.  A stone flung down the Bowery to kill a dog in Broadway.