The Collaborative International Dictionary of English v.0.48:

Encephalopathy \En*ceph`a*lop"a*thy\, n. [Gr. 'egke`falos the
   brain + pa`schein, paqei^n, to suffer.] (Med.)
   Any disease or symptoms of disease referable to disorders of
   the brain; as, lead encephalopathy, the cerebral symptoms
   attending chronic lead poisoning.
   [1913 Webster]

WordNet (r) 3.0 (2006):

encephalopathy
    n 1: any disorder or disease of the brain [syn: brain
         disorder, encephalopathy, brain disease]