The Collaborative International Dictionary of English v.0.48:

disoriented \disoriented\ adj.
   1. having lost one's bearings physically or mentally. I
      frequently find myself disoriented when I come up out of
      the subway;the anesthetic left her completely disoriented

   Syn: confused, lost.
        [WordNet 1.5]

   2. socially disoriented; withdrawn from social interactions.

   Syn: alienated, anomic.
        [WordNet 1.5 +PJC]

WordNet (r) 3.0 (2006):

disoriented
    adj 1: having lost your bearings; confused as to time or place
           or personal identity; "I frequently find myself
           disoriented when I come up out of the subway"; "the
           anesthetic left her completely disoriented" [syn:
           confused, disoriented, lost]
    2: socially disoriented; "anomic loners musing over their fate";
       "we live in an age of rootless alienated people" [syn:
       alienated, anomic, disoriented]

Moby Thesaurus II by Grady Ward, 1.0:

79 Moby Thesaurus words for "disoriented":
   abashed, abnormal, abroad, adrift, astray, at sea,
   bereft of reason, bewildered, bothered, brainsick, clueless,
   confused, crackbrained, cracked, crazed, crazy, daft, deluded,
   demented, deprived of reason, deranged, discomposed, disconcerted,
   dismayed, distracted, distraught, disturbed, embarrassed, flighty,
   guessing, hallucinated, in a fix, in a maze, in a pickle,
   in a scrape, in a stew, insane, irrational, loco, lost, lunatic,
   mad, maddened, manic, mazed, mental, mentally deficient, meshuggah,
   moon-struck, non compos, non compos mentis, not all there,
   not right, odd, of unsound mind, off, off the track, perturbed,
   psycho, put-out, queer, reasonless, senseless, sick, stark-mad,
   stark-staring mad, strange, tetched, touched, turned around,
   unbalanced, unhinged, unsane, unsettled, unsound, upset, wandering,
   without a clue, witless