The Collaborative International Dictionary of English v.0.48:

Bitch \Bitch\ (b[i^]ch), n. [OE. biche, bicche, AS. bicce; cf.
   Icel. bikkja, G. betze, peize.]
   1. The female of the canine kind, as of the dog, wolf, and
      fox.
      [1913 Webster]

   2. An opprobrious name for a woman, especially a lewd woman.
      --Pope.
      [1913 Webster]

   3. an unpleasant, malicious, or offensive person.
      [PJC]

   4. something difficult or unpleasant. [slang]
      [PJC]

   5. a complaint. [slang]
      [PJC]

The Collaborative International Dictionary of English v.0.48:

Bitch \Bitch\ (b[i^]ch), v. i.
   to complain in a whining or grumbling manner; to gripe.
   [slang]
   [PJC]

WordNet (r) 3.0 (2006):

bitch
    n 1: an unpleasant difficulty; "this problem is a real bitch"
    2: a person (usually but not necessarily a woman) who is
       thoroughly disliked; "she said her son thought Hillary was a
       bitch" [syn: cunt, bitch]
    3: informal terms for objecting; "I have a gripe about the
       service here" [syn: gripe, kick, beef, bitch,
       squawk]
    4: female of any member of the dog family
    v 1: complain; "What was he hollering about?" [syn: gripe,
         bitch, grouse, crab, beef, squawk, bellyache,
         holler]
    2: say mean things [syn: backbite, bitch]

Moby Thesaurus II by Grady Ward, 1.0:

260 Moby Thesaurus words for "bitch":
   Augean task, Herculean task, Jane, Jezebel, Partlet,
   Seeing Eye dog, air a grievance, backbreaker, bad woman, baggage,
   ballbuster, bandog, battle-ax, bawd, beef, beefing, beguile,
   beldam, bellyache, bellyaching, betray, biddy, bimbo, bird,
   bitch up, bitching, bleat, bluff, bobble, boggle, bonehead into it,
   bossy, botch, bowwow, boycott, broad, brood mare, bugger,
   bugger up, bungle, call in question, canine, cat, challenge, chick,
   chippy, chore, clamor, clitoromaniac, cocotte, common scold,
   complain, complaining, complaint, compunction, cow, crab, crib,
   croak, cry out against, dame, dead lift, delude, demonstrate,
   demonstrate against, demonstration, demur, demurrer,
   destructive criticism, dispute, dissent, doe, dog, doll,
   double-cross, drab, drop a brick, easy lay, easy woman,
   enter a protest, ewe, ewe lamb, exception, expostulate,
   expostulation, fancy dog, faultfinding, filly, fishwife, floozie,
   floozy, flub, foul up, four-flush, frail sister, fret,
   fret and fume, fury, fuss, goof, goof up, grievance,
   grievance committee, gripe, griping, grisette, groan, groaning,
   grouch, grouse, grousing, growl, grumble, grumbling, grump, grunt,
   guide dog, guinea hen, gum up, gyp, handful, hard job, hard pull,
   harlot, harpy, harridan, hash up, heavy sledding, heifer, hen,
   hind, holler, hooker, howl, humbug, hussy, hustler, hysteromaniac,
   indignation meeting, jade, jenny, juggle, kennel, kick, kicking,
   lap dog, large order, lioness, lodge a complaint, loose woman,
   louse up, man-sized job, march, mare, mess up, minx, mope, murmur,
   murmuring, mutter, nag, nanny, nanny goat, nonviolent protest,
   nymphet, nympho, nymphomaniac, object, objection, pack of dogs,
   peahen, peeve, peevishness, pet peeve, petulance, picket,
   picketing, pickup, pooch, press objections, pro, prostitute,
   protest, protest demonstration, protestation, pup, puppy, qualm,
   quean, querulousness, raise a howl, rally, register a complaint,
   remonstrance, remonstrate, remonstration, roe, rough go, ruin,
   scold, scolding, screw up, scruple, she-bear, she-devil, she-goat,
   she-lion, she-wolf, sheep dog, show dog, shrew, sit in, sit-in,
   skirt, sled dog, slut, sniping, sow, spitfire, spoil, squawk,
   squawking, state a grievance, streetwalker, strike, strumpet, sulk,
   take in, take on, tall order, tart, teach in, teach-in, termagant,
   tigress, tomato, tough job, tough proposition, toy dog, tramp,
   trollop, trull, uphill work, uteromaniac, virago, vixen, wanton,
   watchdog, wench, whelp, whining, whore, witch, working dog, yammer,
   yap, yapping, yawp, yell bloody murder, yelp