The Collaborative International Dictionary of English v.0.48:

Deranged \De*ranged"\, a.
   Disordered; especially, disordered in mind; crazy; insane.
   [1913 Webster]

         The story of a poor deranged parish lad. --Lamb.
   [1913 Webster]

The Collaborative International Dictionary of English v.0.48:

Derange \De*range"\, v. t. [imp. & p. p. Deranged; p. pr. &
   vb. n. Deranging.] [F. d['e]ranger; pref. d['e]- = d['e]s-
   (L. dis) + ranger to range. See Range, and cf.
   Disarrange, Disrank.]
   1. To put out of place, order, or rank; to disturb the proper
      arrangement or order of; to throw into disorder,
      confusion, or embarrassment; to disorder; to disarrange;
      as, to derange the plans of a commander, or the affairs of
      a nation.
      [1913 Webster]

   2. To disturb in action or function, as a part or organ, or
      the whole of a machine or organism.
      [1913 Webster]

            A sudden fall deranges some of our internal parts.
                                                  --Blair.
      [1913 Webster]

   3. To disturb in the orderly or normal action of the
      intellect; to render insane.

   Syn: To disorder; disarrange; displace; unsettle; disturb;
        confuse; discompose; ruffle; disconcert.
        [1913 Webster]

WordNet (r) 3.0 (2006):

deranged
    adj 1: driven insane [syn: crazed, deranged, half-crazed]

Moby Thesaurus II by Grady Ward, 1.0:

102 Moby Thesaurus words for "deranged":
   abnormal, amiss, askew, awry, balmy, bananas, barmy, bats, batty,
   bereft of reason, berserk, bonkers, brainsick, cockeyed, convulsed,
   crackbrained, cracked, crazed, crazy, cuckoo, daft, deluded,
   demented, deprived of reason, dippy, disarranged, discomfited,
   discomposed, disconcerted, dislocated, disordered, disorderly,
   disorganized, disoriented, distraught, disturbed, dotty, flighty,
   hallucinated, haywire, in disorder, insane, irrational, kooky,
   loco, loony, lunatic, mad, maddened, maniac, manic, mazed, mental,
   mentally deficient, meshuggah, misplaced, moon-struck, non compos,
   non compos mentis, not all there, not right, nuts, nutty, odd,
   of unsound mind, off, on the fritz, out of gear, out of joint,
   out of kelter, out of kilter, out of order, out of place,
   out of tune, out of whack, perturbed, potty, psycho, psychotic,
   queer, reasonless, roily, screwy, senseless, shuffled, sick,
   stark-mad, stark-staring mad, strange, tetched, touched, turbid,
   turbulent, unbalanced, unhinged, unsane, unsettled, unsound, upset,
   wacky, wandering, witless