The Collaborative International Dictionary of English v.0.48:

Bother \Both"er\, v. t. [imp. & p. p. Bothered (?); p. pr. &
   vb. n. Bothering.] [Cf. Ir. buaidhirt trouble, buaidhrim I
   vex.]
   To annoy; to trouble; to worry; to perplex. See Pother.
   [1913 Webster]

   Note: The imperative is sometimes used as an exclamation
         mildly imprecatory.
         [1913 Webster]