The Collaborative International Dictionary of English v.0.48:

Sophistication \So*phis`ti*ca"tion\, n. [Cf. LL. sophisticatio,
   F. sophistication.]
   The act of sophisticating; adulteration; as, the
   sophistication of drugs. --Boyle.
   [1913 Webster]

WordNet (r) 3.0 (2006):

sophistication
    n 1: uplifting enlightenment [syn: edification,
         sophistication]
    2: a deliberately invalid argument displaying ingenuity in
       reasoning in the hope of deceiving someone [syn: sophism,
       sophistry, sophistication]
    3: being expert or having knowledge of some technical subject;
       "understanding affine transformations requires considerable
       mathematical sophistication"
    4: the quality or character of being intellectually
       sophisticated and worldly through cultivation or experience
       or disillusionment [syn: sophistication, worldliness,
       mundaneness, mundanity] [ant: naiveness, naivete,
       naivety]
    5: falsification by the use of sophistry; misleading by means of
       specious fallacies; "he practiced the art of sophistication
       upon reason"