The Collaborative International Dictionary of English v.0.48:

Insalubrious \In`sa*lu"bri*ous\, a. [Pref. in- not + salubrious:
   cf. L. insalubris, F. insalubre.]
   Not salubrious or healthful; unwholesome; as, an insalubrious
   air or climate.
   [1913 Webster]

WordNet (r) 3.0 (2006):

insalubrious
    adj 1: detrimental to health [syn: insalubrious,
           unhealthful, unhealthy]