The Collaborative International Dictionary of English v.0.48:

Despoil \De*spoil"\, v. t. [imp. & p. p. Despoiled; p. pr. &
   vb. n. Despoiling.] [OF. despoiller, F. d['e]pouiller, L.
   despoliare, despoliatum; de- + spoliare to strip, rob,
   spolium spoil, booty. Cf. Spoil, Despoliation.]
   1. To strip, as of clothing; to divest or unclothe. [Obs.]
      --Chaucer.
      [1913 Webster]

   2. To deprive for spoil; to plunder; to rob; to pillage; to
      strip; to divest; -- usually followed by of.
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            The clothed earth is then bare,
            Despoiled is the summer fair.         --Gower.
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            A law which restored to them an immense domain of
            which they had been despoiled.        --Macaulay.
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            Despoiled of innocence, of faith, of bliss.
                                                  --Milton.

   Syn: To strip; deprive; rob; bereave; rifle.
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The Collaborative International Dictionary of English v.0.48:

despoil \de*spoil"\, n.
   Spoil. [Obs.] --Wolsey.
   [1913 Webster]

WordNet (r) 3.0 (2006):

despoil
    v 1: steal goods; take as spoils; "During the earthquake people
         looted the stores that were deserted by their owners" [syn:
         plunder, despoil, loot, reave, strip, rifle,
         ransack, pillage, foray]
    2: destroy and strip of its possession; "The soldiers raped the
       beautiful country" [syn: rape, spoil, despoil,
       violate, plunder]