The Collaborative International Dictionary of English v.0.48:

Discomfort \Dis*com"fort\, v. t. [imp. & p. p. Discomforted;
   p. pr. & vb. n. Discomforting.] [OF. desconforter, F.
   d['e]conforter, to discourage; pref. des- (L dis-) +
   conforter. See Comfort.]
   1. To discourage; to deject.
      [1913 Webster]

            His funeral shall not be in our camp,
            Lest it discomfort us.                --Shak.
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   2. To destroy or disturb the comfort of; to deprive of quiet
      enjoyment; to make uneasy; to pain; as, a smoky chimney
      discomforts a family.
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The Collaborative International Dictionary of English v.0.48:

Discomfort \Dis*com"fort\, n. [OF. desconfort, F. d['e]confort.
   See Discomfort, v. t.]
   1. Discouragement. [Obs.] --Shak.
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   2. Want of comfort; uneasiness, mental or physical;
      disturbance of peace; inquietude; pain; distress; sorrow.
      "An age of spiritual discomfort." --M. Arnold.
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            Strive against all the discomforts of thy
            sufferings.                           --Bp. Hall.
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WordNet (r) 3.0 (2006):

discomfort
    n 1: the state of being tense and feeling pain [syn:
         discomfort, uncomfortableness] [ant: comfort,
         comfortableness]
    2: an uncomfortable feeling of mental painfulness or distress
       [syn: discomfort, soreness, irritation]