The Collaborative International Dictionary of English v.0.48:

Wrinkle \Wrin"kle\, v. t. [imp. & p. p. Wrinkled; p. pr. & vb.
   n. Wrinkling.]
   [1913 Webster]
   1. To contract into furrows and prominences; to make a
      wrinkle or wrinkles in; to corrugate; as, wrinkle the skin
      or the brow. "Sport that wrinkled Care derides." --Milton.
      [1913 Webster]

            Her wrinkled form in black and white arrayed.
                                                  --Pope.
      [1913 Webster]

   2. Hence, to make rough or uneven in any way.
      [1913 Webster]

            A keen north wind that, blowing dry,
            Wrinkled the face of deluge, as decayed. --Milton.
      [1913 Webster]

            Then danced we on the wrinkled sand.  --Bryant.
      [1913 Webster]

   To wrinkle at, to sneer at. [Obs.] --Marston.
      [1913 Webster]

The Collaborative International Dictionary of English v.0.48:

Wrinkle \Wrin"kle\, n.
   A winkle. [Local, U. S.]
   [1913 Webster]

The Collaborative International Dictionary of English v.0.48:

Wrinkle \Wrin"kle\, n. [OE. wrinkil, AS. wrincle; akin to OD.
   wrinckel, and prob. to Dan. rynke, Sw. rynka, Icel. hrukka,
   OHG. runza, G. runzel, L. ruga. ????.]
   [1913 Webster]
   1. A small ridge, prominence, or furrow formed by the
      shrinking or contraction of any smooth substance; a
      corrugation; a crease; a slight fold; as, wrinkle in the
      skin; a wrinkle in cloth. "The wrinkles in my brows."
      --Shak.
      [1913 Webster]

            Within I do not find wrinkles and used heart, but
            unspent youth.                        --Emerson.
      [1913 Webster]

   2. hence, any roughness; unevenness.
      [1913 Webster]

            Not the least wrinkle to deform the sky. --Dryden.
      [1913 Webster]

   3. [Perhaps a different word, and a dim. AS. wrenc a
      twisting, deceit. Cf. Wrench, n.] A notion or fancy; a
      whim; as, to have a new wrinkle. [Colloq.]
      [1913 Webster]

The Collaborative International Dictionary of English v.0.48:

Wrinkle \Wrin"kle\, v. i.
   To shrink into furrows and ridges.
   [1913 Webster]

WordNet (r) 3.0 (2006):

wrinkle
    n 1: a slight depression in the smoothness of a surface; "his
         face has many lines"; "ironing gets rid of most wrinkles"
         [syn: wrinkle, furrow, crease, crinkle, seam,
         line]
    2: a minor difficulty; "they finally have the wrinkles pretty
       well ironed out"
    3: a clever method of doing something (especially something new
       and different)
    v 1: gather or contract into wrinkles or folds; pucker; "purse
         ones's lips" [syn: purse, wrinkle]
    2: make wrinkles or creases on a smooth surface; make a pressed,
       folded or wrinkled line in; "The dress got wrinkled"; "crease
       the paper like this to make a crane" [syn: wrinkle,
       ruckle, crease, crinkle, scrunch, scrunch up,
       crisp]
    3: make wrinkled or creased; "furrow one's brow" [syn: furrow,
       wrinkle, crease]
    4: become wrinkled or crumpled or creased; "This fabric won't
       wrinkle" [syn: rumple, crumple, wrinkle, crease,
       crinkle]

Moby Thesaurus II by Grady Ward, 1.0:

146 Moby Thesaurus words for "wrinkle":
   abbreviate, age, bezel, bonus, bristle, canal, canalize, carve,
   chamfer, channel, chase, cheat the undertaker, chink, chisel,
   circumscribe, coarct, cocker, cockle, compact, compress,
   concentrate, condense, consolidate, constrict, constringe,
   contract, corrugate, corrugation, crack, cramp, crankle, cranny,
   craze, crease, crimp, crimple, crinkle, crumple, curtail, cut,
   dado, decline, decoration, decrease, dike, ditch, dodder, draw,
   draw in, draw together, engrave, engraving, extra,
   extra added attraction, extra dash, fad, faddiness, faddishness,
   faddism, faddist, fade, fail, filigree, filling, fillip, flourish,
   flute, fluting, fold, frill, furrow, gash, get along, get on,
   goffer, gouge, groove, grow old, gully, incise, incision, knit,
   knot, lagniappe, microgroove, narrow, novelty, ornament, padding,
   pleat, plica, plow, premium, pucker, pucker up, purse, rabbet,
   rage, reduce, ridge, rifle, rifling, rimple, ripple, rivel, ruck,
   ruckle, ruffle, rumple, rut, score, scratch, screw, scrunch,
   set on edge, shake, shirr, shorten, shrivel, sink, slit, solidify,
   something extra, strangle, strangulate, streak, stria, striate,
   striation, stuffing, sulcation, sulcus, superaddition, totter,
   trench, trimming, trough, turn gray, turn white, twist, wane,
   waste away, well-worn groove, wimple, wither, wizen