WordNet (r) 3.0 (2006):

whammy
    n 1: a serious or devastating setback
    2: an evil spell; "a witch put a curse on his whole family"; "he
       put the whammy on me" [syn: hex, jinx, curse, whammy]

Moby Thesaurus II by Grady Ward, 1.0:

80 Moby Thesaurus words for "whammy":
   Jonah, amulet, anathema, bad blood, bad influence, bad temper,
   bad will, ban, bedroom eyes, blasphemy, blighting glance,
   bring bad luck, cantrip, charm, come-hither look, commination,
   curse, damnation, denunciation, enchantment, evil disposition,
   evil eye, evil genius, evil star, excommunication, execration,
   exorcism, fetish, fulmination, fylfot, gammadion, gape, gaze,
   glad eye, glamour, glare, glower, glowering look, goggle,
   good-luck charm, hex, hoodoo, ill nature, ill will, ill wind,
   ill-disposedness, imprecation, jinx, juju, love charm, lucky bean,
   lucky piece, madstone, magic spell, malevolence,
   malevolent influence, malison, malocchio, mascot, mumbo jumbo,
   obeah, ogle, penetrating look, periapt, philter, phylactery,
   proscription, scarab, scarabaeus, scarabee, spell, stare, sudarium,
   swastika, talisman, thundering, veronica, voodoo, wanga, weird