The Collaborative International Dictionary of English v.0.48:

Pother \Poth"er\, v. t. [imp. & p. p. Pothered; p. pr. & vb.
   n. Pothering.]
   To harass and perplex; to worry. "Pothers and wearies
   himself." --Locke.
   [1913 Webster]

The Collaborative International Dictionary of English v.0.48:

Pother \Poth"er\, n. [Cf. D. peuteren to rummage, poke. Cf.
   Potter, Pudder.]
   Bustle; confusion; tumult; flutter; bother. [Written also
   potter, and pudder.] "What a pother and stir!" --Oldham.
   "Coming on with a terrible pother." --Wordsworth.
   [1913 Webster]

The Collaborative International Dictionary of English v.0.48:

Pother \Poth"er\, v. i.
   To make a bustle or stir; to be fussy.
   [1913 Webster]

WordNet (r) 3.0 (2006):

pother
    n 1: an excited state of agitation; "he was in a dither"; "there
         was a terrible flap about the theft" [syn: dither,
         pother, fuss, tizzy, flap]
    v 1: make upset or troubled
    2: make a fuss; be agitated [syn: dither, flap, pother]

Moby Thesaurus II by Grady Ward, 1.0:

220 Moby Thesaurus words for "pother":
   abash, addle, addle the wits, ado, aggravate, aggravation,
   agitation, ail, annoy, badger, baffle, bafflement, bait, ball up,
   be at, be the matter, becloud, bedazzle, bedevil, befuddle,
   befuddlement, beset, bewilder, bewilderment, bother, botheration,
   brawl, bristle, broil, brouhaha, brown off, bug, bullyrag, burn up,
   burst, bustle, chaos, chivy, clamor, cloud, commotion,
   complicate matters, concern, confoundment, confuse, confusion,
   daze, dazzle, devil, dilemma, discombobulate, discombobulation,
   discomfit, discomfiture, discommode, discompose, discomposure,
   disconcert, disconcertedness, disconcertion, disconcertment,
   dismay, disorder, disorganization, disorganize, disorient,
   disorientation, distemper, distress, disturb, disturbance, dither,
   dog, donnybrook, donnybrook fair, dustup, embarrass, embarrassment,
   embroilment, enigma, entangle, exasperate, exasperation, exercise,
   fash, feery-fary, ferment, fidgetiness, fit, fix, flap, flummox,
   flurry, fluster, flusteration, flustration, flutter, flutteriness,
   fog, foofaraw, fracas, free-for-all, frenzy, fret, fuddle,
   fuddlement, furore, fuss, fussiness, get, gripe, harass, harry,
   hassle, haze, heckle, hector, helter-skelter, hound, hubbub,
   hullabaloo, hurly-burly, inconvenience, irk, jam, jumble, lather,
   maelstrom, maze, melee, mess, miff, mist, mix up, moider, molest,
   muddle, muddlement, mystery, nag, needle, nettle, nonplus, nudzh,
   peeve, pell-mell, perplex, perplexity, persecute, perturb,
   perturbation, pester, pick on, pickle, pique, plague, plight,
   pluck the beard, predicament, problem, provoke, pucker, put out,
   put to it, puzzle, puzzlement, quandary, racket, raise hell,
   rampage, rattle, restlessness, riddle, ride, rile, riot, roil,
   rough-and-tumble, roughhouse, row, ruckus, ruction, ruffle, rumpus,
   scramble, scrape, shindy, shuffle, spasm, spurt, stew, stir, sweat,
   swirl, swivet, tease, throw into confusion, tizzy, to-do, torment,
   trouble, try the patience, tumult, turbulence, turmoil,
   tweak the nose, twitter, twitteration, unassuredness, unquiet,
   unsettle, unsettlement, uproar, upset, vex, vortex, whirl,
   whirlpool, whirlwind, worry