The Collaborative International Dictionary of English v.0.48:

Loose \Loose\ (l[=oo]s), a. [Compar. Looser (l[=oo]s"[~e]r);
   superl. Loosest.] [OE. loos, lous, laus, Icel. lauss; akin
   to OD. loos, D. los, AS. le['a]s false, deceitful, G. los,
   loose, Dan. & Sw. l["o]s, Goth. laus, and E. lose. [root]127.
   See Lose, and cf. Leasing falsehood.]
   1. Unbound; untied; unsewed; not attached, fastened, fixed,
      or confined; as, the loose sheets of a book.
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            Her hair, nor loose, nor tied in formal plat.
                                                  --Shak.
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   2. Free from constraint or obligation; not bound by duty,
      habit, etc.; -- with from or of.
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            Now I stand
            Loose of my vow; but who knows Cato's thoughts ?
                                                  --Addison.
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   3. Not tight or close; as, a loose garment.
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   4. Not dense, close, compact, or crowded; as, a cloth of
      loose texture.
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            With horse and chariots ranked in loose array.
                                                  --Milton.
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   5. Not precise or exact; vague; indeterminate; as, a loose
      style, or way of reasoning.
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            The comparison employed . . . must be considered
            rather as a loose analogy than as an exact
            scientific explanation.               --Whewel.
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   6. Not strict in matters of morality; not rigid according to
      some standard of right.
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            The loose morality which he had learned. --Sir W.
                                                  Scott.
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   7. Unconnected; rambling.
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            Vario spends whole mornings in running over loose
            and unconnected pages.                --I. Watts.
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   8. Lax; not costive; having lax bowels. --Locke.
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   9. Dissolute; unchaste; as, a loose man or woman.
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            Loose ladies in delight.              --Spenser.
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   10. Containing or consisting of obscene or unchaste language;
       as, a loose epistle. --Dryden.
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   At loose ends, not in order; in confusion; carelessly
      managed.

   Fast and loose. See under Fast.

   To break loose. See under Break.

   Loose pulley. (Mach.) See Fast and loose pulleys, under
      Fast.

   To let loose, to free from restraint or confinement; to set
      at liberty.
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The Collaborative International Dictionary of English v.0.48:

Loose \Loose\, n.
   1. Freedom from restraint. [Obs.] --Prior.
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   2. A letting go; discharge. --B. Jonson.
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   To give a loose, to give freedom.
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            Vent all its griefs, and give a loose to sorrow.
                                                  --Addison.
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The Collaborative International Dictionary of English v.0.48:

Loose \Loose\ (l[=oo]s), v. n. [imp. & p. p. Loosed
   (l[=oo]st); p. pr. & vb. n. Loosing.] [From Loose, a.]
   1. To untie or unbind; to free from any fastening; to remove
      the shackles or fastenings of; to set free; to relieve.
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            Canst thou . . . loose the bands of Orion ? --Job.
                                                  xxxviii. 31.
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            Ye shall find an ass tied, and a colt with her;
            loose them, and bring them unto me.   --Matt. xxi.
                                                  2.
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   2. To release from anything obligatory or burdensome; to
      disengage; hence, to absolve; to remit.
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            Art thou loosed from a wife ? seek not a wife. --1
                                                  Cor. vii. 27.
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            Whatsoever thou shalt loose on earth shall be loosed
            in heaven.                            --Matt. xvi.
                                                  19.
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   3. To relax; to loosen; to make less strict.
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            The joints of his loins were loosed.  --Dan. v. 6.
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   4. To solve; to interpret. [Obs.] --Spenser.
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The Collaborative International Dictionary of English v.0.48:

Loose \Loose\, v. i.
   To set sail. [Obs.] --Acts xiii. 13.
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WordNet (r) 3.0 (2006):

loose
    adv 1: without restraint; "cows in India are running loose"
           [syn: loose, free]
    adj 1: not compact or dense in structure or arrangement; "loose
           gravel" [ant: compact]
    2: (of a ball in sport) not in the possession or control of any
       player; "a loose ball"
    3: not tight; not closely constrained or constricted or
       constricting; "loose clothing"; "the large shoes were very
       loose" [ant: tight]
    4: not officially recognized or controlled; "an informal
       agreement"; "a loose organization of the local farmers" [syn:
       informal, loose]
    5: not literal; "a loose interpretation of what she had been
       told"; "a free translation of the poem" [syn: free,
       loose, liberal]
    6: emptying easily or excessively; "loose bowels" [syn: lax,
       loose]
    7: not affixed; "the stamp came loose" [syn: unaffixed,
       loose] [ant: affixed]
    8: not tense or taut; "the old man's skin hung loose and grey";
       "slack and wrinkled skin"; "slack sails"; "a slack rope"
       [syn: loose, slack]
    9: (of textures) full of small openings or gaps; "an open
       texture"; "a loose weave" [syn: loose, open]
    10: lacking a sense of restraint or responsibility; "idle talk";
        "a loose tongue" [syn: idle, loose]
    11: not carefully arranged in a package; "a box of loose nails"
    12: having escaped, especially from confinement; "a convict
        still at large"; "searching for two escaped prisoners";
        "dogs loose on the streets"; "criminals on the loose in the
        neighborhood" [syn: at large(p), escaped, loose, on
        the loose(p)]
    13: casual and unrestrained in sexual behavior; "her easy
        virtue"; "he was told to avoid loose (or light) women";
        "wanton behavior" [syn: easy, light, loose,
        promiscuous, sluttish, wanton]
    v 1: grant freedom to; free from confinement [syn: free,
         liberate, release, unloose, unloosen, loose]
         [ant: confine, detain]
    2: turn loose or free from restraint; "let loose mines"; "Loose
       terrible plagues upon humanity" [syn: unleash, let loose,
       loose]
    3: make loose or looser; "loosen the tension on a rope" [syn:
       loosen, loose] [ant: stiffen]
    4: become loose or looser or less tight; "The noose loosened";
       "the rope relaxed" [syn: loosen, relax, loose] [ant:
       stiffen]

Moby Thesaurus II by Grady Ward, 1.0:

467 Moby Thesaurus words for "loose":
   Bohemian, Paphian, abandoned, abate, absonant, adrift, affable,
   afloat, afoot and lighthearted, aid, aimless, aleatoric, aleatory,
   alleviate, amorphous, approximate, approximative, at large,
   at liberty, aweigh, bagging, baggy, ballooning, barbarous, bate,
   beat-up, bedraggled, blobby, blowzy, blurred, blurry, break loose,
   broad, by the way, capricious, careless, cast off, cast-off,
   casual, chambering, chance, chancy, chaotic, chintzy, clear,
   clear the way, confused, contradictory, contrary to reason,
   cool off, cordial, corrupt, culpably negligent, dangling,
   debauched, degage, deliver, derelict, desultory, detach, detached,
   deviative, diffuse, digressive, dilapidated, discharge,
   disconnected, discontinuous, discursive, disengage, disengaged,
   disenthrall, disjoin, disjointed, disordered, disorganized,
   disperse, dispersed, dissolute, doff, drabbletailed, draggled,
   draggletailed, drooping, droopy, ease, ease off, ease up, easy,
   easygoing, emancipate, emancipated, emit, episodic, erroneous,
   escape, escaped, excursive, expedite, explain, extravagant,
   facilitate, fallacious, familiar, fast, faulty, fire, flabby,
   flaccid, flapping, flawed, fled, flee, flimsy, floating, floppy,
   flowing, flown, foggy, folksy, footloose, footloose and fancy-free,
   free, free and easy, free as air, freeborn, freed, frowzy,
   frumpish, frumpy, fugitive, fuzzy, general, give out with,
   go-as-you-please, go-go, gracious, grease, grease the ways,
   grease the wheels, grubby, hanging, hasten, haymish, hazy,
   help along, hit-or-miss, homely, homey, ill-defined, illogical,
   immoderate, immoral, impotent, imprecise, improper, in disarray,
   in disorder, in rags, in the clear, inaccurate, inadvertent,
   inattentive, inauthentic, inchoate, incoherent, inconclusive,
   incongruous, inconsequent, inconsequential, inconsistent,
   inconstant, incontinent, incorrect, indecisive, indefinable,
   indefinite, indeterminable, indeterminate, indifferent, indistinct,
   indulgent, inexact, infelicitous, informal, intemperate, invalid,
   irrational, irregular, irrepressible, laissez-faire, lax, lenient,
   lessen, let down, let fly, let go, let up, lewd, liberate,
   liberated, libertine, licentious, light, limp, loose-moraled,
   loosen, lop, lop-eared, loppy, lubricate, lumpen, make clear,
   make way for, manumit, maundering, messy, mitigate, movable, mussy,
   natural, neglectful, neglecting, negligent, nodding, nonadhesive,
   noninterfering, nonrestrictive, nonscientific, nonspecific,
   not following, obscure, of easy virtue, of loose morals, off-guard,
   offhand, offhanded, oil, on the loose, open the way, open up,
   orderless, out of, out of control, out of hand, out of line,
   out of plumb, out of square, out of true, overindulgent,
   overly permissive, overpermissive, paralogical, pave the way,
   permissive, perverted, plain, poky, prepare the way,
   procrastinating, profligate, promiscuous, quicken, ragged, raggedy,
   rambling, rampant, random, reasonless, reckless, reinless, relax,
   relaxed, release, released, remiss, remit, remove, remove friction,
   rickety, riotous, rough, roving, rubbery, ruinous,
   run interference for, runaway, sagging, sagging in folds, saggy,
   scamping, scatter, scot-free, scraggly, seedy, self-annulling,
   self-contradictory, self-refuting, senseless, separate, set free,
   shabby, shadowed forth, shadowy, shaky, shapeless, shoddy, shoot,
   simple, simplify, sit back, skimping, slack, slack off, slack up,
   slacken, slake, slapdash, slatternly, slighting, slipshod, sloppy,
   slovenly, slurring, sluttish, smooth, smooth the way,
   soap the ways, sociable, soft, solecistic, sordid, speed,
   spread about, squalid, started, stochastic, streaming, swag,
   sweeping, tacky, take it easy, take off, tattered, unaffected,
   unanchored, unassuming, unattached, unauthentic, unbar, unbend,
   unbind, unblock, unbolt, unbound, unbrace, unbridle, unbridled,
   unbuckle, unbutton, uncage, unceremonious, unchain, unchained,
   unchaste, unchecked, uncircumspect, unclasp, unclear, unclog,
   uncoerced, uncommitted, uncompelled, unconfined, unconnected,
   unconstrained, uncontrolled, unconventional, uncurbed, undefined,
   undestined, undetermined, undo, undone, unengaged, unfactual,
   unfasten, unfastened, unfetter, unfettered, unfixed, unforced,
   ungag, unglue, ungoverned, ungrammatic, unguarded, unhandcuff,
   unhobble, uninhibited, uninvolved, unjam, unkempt, unlace, unlash,
   unlatch, unleash, unlock, unloose, unloosen, unmanacle, unmastered,
   unmeasured, unmoored, unmuzzle, unmuzzled, unneat, unofficial,
   unpen, unphilosophical, unpinion, unplain, unprecise, unreasonable,
   unreined, unrepressed, unreserved, unrestrained, unrestrictive,
   unrigorous, unruly, unscientific, unsecured, unshackle, unshackled,
   unsightly, unspecific, unspecified, unstick, unstrain, unstrap,
   unstring, unstuck, unstudied, unsubdued, unsuppressed, untether,
   untidy, untie, untied, untighten, untruss, unwary, unwatchful,
   unyoke, vague, veiled, vent, wandering, wanton, wayward, weak,
   weigh anchor, well out of, whorish, wild, without reason