The Collaborative International Dictionary of English v.0.48:

Fretful \Fret"ful\, a. [See 2d Fret.]
   Disposed to fret; ill-humored; peevish; angry; in a state of
   vexation; as, a fretful temper. -- Fret"ful*ly, adv. --
   Fret"ful*ness, n.

   Syn: Peevish; ill-humored; ill-natured; irritable; waspish;
        captious; petulant; splenetic; spleeny; passionate;
        angry.

   Usage: Fretful, Peevish, Cross. These words all
          indicate an unamiable working and expression of
          temper. Peevish marks more especially the inward
          spirit: a peevish man is always ready to find fault.
          Fretful points rather to the outward act, and marks a
          complaining impatience: sickly children are apt to be
          fretful. Crossness is peevishness mingled with
          vexation or anger.
          [1913 Webster]

WordNet (r) 3.0 (2006):

fretful
    adj 1: nervous and unable to relax; "a constant fretful stamping
           of hooves"; "a restless child" [syn: antsy, fidgety,
           fretful, itchy]
    2: habitually complaining; "a whiny child" [syn: fretful,
       querulous, whiney, whiny]

Moby Thesaurus II by Grady Ward, 1.0:

93 Moby Thesaurus words for "fretful":
   Jeremianic, abrupt, agitated, antsy, antsy-pantsy, anxious,
   bad-tempered, breathless, bustling, captious, carping, catty,
   caviling, chafing, choleric, complaining, contrary, crabby, cranky,
   critical, cross, curt, disagreeable, eager, edgy, excited,
   faultfinding, fidgety, fluttering, fluttery, fractious, fretting,
   fussing, fussy, grumpy, hasty, hopped-up, howling, huffy,
   ill-natured, ill-tempered, impatient, impetuous, in a lather,
   in a stew, in a sweat, irascible, irritable, jumpy, lamentive,
   moanful, moody, mournful, nagging, naggy, on edge, peevish,
   perverse, pettish, petulant, plaintive, plangent, puling,
   querulous, resentful, restive, restless, short, short-tempered,
   shrewish, snappish, sorrowful, splenetic, squirming, squirmy,
   sulky, testy, tetchy, touchy, turbulent, ululant, uneasy,
   unpatient, unquiet, unsettled, vexed, vixenish, vixenly, wailful,
   waspish, whimpering, whining, whiny