The Collaborative International Dictionary of English v.0.48:

Resign \Re*sign"\ (r?-z?n"), v. t. [imp. & p. p. Resigned
   (-z?nd"); p. pr. & vb. n. Resigning.] [F. r['e]signer, L.
   resignare to unseal, annul, assign, resign; pref. re- re- +
   signare to seal, stamp. See Sign, and cf. Resignation.]
   [1913 Webster]
   1. To sign back; to return by a formal act; to yield to
      another; to surrender; -- said especially of office or
      emolument. Hence, to give up; to yield; to submit; -- said
      of the wishes or will, or of something valued; -- also
      often used reflexively.
      [1913 Webster]

            I here resign my government to thee.  --Shak.
      [1913 Webster]

            Lament not, Eve, but patiently resign
            What justly thou hast lost.           --Milton.
      [1913 Webster]

            What more reasonable, than that we should in all
            things resign up ourselves to the will of God?
                                                  --Tiilotson.
      [1913 Webster]

   2. To relinquish; to abandon.
      [1913 Webster]

            He soon resigned his former suit.     --Spenser.
      [1913 Webster]

   3. To commit to the care of; to consign. [Obs.]
      [1913 Webster]

            Gentlement of quality have been sent beyong the
            seas, resigned and concredited to the conduct of
            such as they call governors.          --Evelyn.
      [1913 Webster]

   Syn: To abdicate; surrender; submit; leave; relinquish;
        forego; quit; forsake; abandon; renounce.

   Usage: Resign, Relinquish. To resign is to give up, as if
          breaking a seal and yielding all it had secured;
          hence, it marks a formal and deliberate surrender. To
          relinquish is less formal, but always implies
          abandonment and that the thing given up has been long
          an object of pursuit, and, usually, that it has been
          prized and desired. We resign what we once held or
          considered as our own, as an office, employment, etc.
          We speak of relinquishing a claim, of relinquishing
          some advantage we had sought or enjoyed, of
          relinquishing seme right, privilege, etc. "Men are
          weary with the toil which they bear, but can not find
          it in their hearts to relinquish it." --Steele. See
          Abdicate.
          [1913 Webster]

The Collaborative International Dictionary of English v.0.48:

Re-sign \Re-sign"\ (r?-s?n"), v. t. [Pref. re- + sign.]
   To affix one's signature to, a second time; to sign again.
   [1913 Webster]

WordNet (r) 3.0 (2006):

resign
    v 1: leave (a job, post, or position) voluntarily; "She vacated
         the position when she got pregnant"; "The chairman resigned
         when he was found to have misappropriated funds" [syn:
         vacate, resign, renounce, give up]
    2: give up or retire from a position; "The Secretary of the Navy
       will leave office next month"; "The chairman resigned over
       the financial scandal" [syn: leave office, quit, step
       down, resign] [ant: take office]
    3: part with a possession or right; "I am relinquishing my
       bedroom to the long-term house guest"; "resign a claim to the
       throne" [syn: release, relinquish, resign, free,
       give up]
    4: accept as inevitable; "He resigned himself to his fate" [syn:
       resign, reconcile, submit]

Moby Thesaurus II by Grady Ward, 1.0:

113 Moby Thesaurus words for "resign":
   abandon, abdicate, abjure, accede, accept, acknowledge defeat,
   acquiesce, assent, be agreeable, be pensioned, be superannuated,
   cease, cede, circulate, come across with, come off, comply,
   consent, cry quits, cut out, deliver, deliver over, demit, desist,
   desist from, discontinue, disgorge, dispense with, dispose of,
   distribute, disuse, do without, drop, dump, face the music, forgo,
   fork over, forsake, forswear, forward, get along without,
   get rid of, give away, give in, give notice, give out, give over,
   give up, go, go along with, hand, hand in, hand out, hand over,
   have done with, kiss good-bye, knock under, knuckle down,
   knuckle under, lay down, leave, leave off, let go, live with it,
   make a sacrifice, nol-pros, not pursue with, not resist, obey,
   part with, pass, pass out, pass over, pension off, put behind one,
   quit, quitclaim, reach, recant, release, relent, relinquish,
   render, render up, renounce, renounce the throne, retire,
   retire from office, retract, sacrifice, spare, stand aside,
   stand down, step aside, stop, submit, succumb, superannuate,
   surrender, swallow it, swallow the pill, swear off, take, take it,
   terminate, throw up, transfer, turn over, turn up, vacate, waive,
   withdraw from, yield



The Devil's Dictionary (1881-1906):

RESIGN, v.t.  To renounce an honor for an advantage.  To renounce an
advantage for a greater advantage.

    'Twas rumored Leonard Wood had signed
        A true renunciation
    Of title, rank and every kind
        Of military station --
        Each honorable station.

    By his example fired -- inclined
        To noble emulation,
    The country humbly was resigned
        To Leonard's resignation --
        His Christian resignation.
                                                       Politian Greame