The Collaborative International Dictionary of English v.0.48:

Jade \Jade\, v. t. [imp. & p. p. Jaded; p. pr. & vb. n.
   Jading.]
   [1913 Webster]
   1. To treat like a jade; to spurn. [Obs.] --Shak.
      [1913 Webster]

   2. To make ridiculous and contemptible. [Obs.]
      [1913 Webster]

            I do now fool myself, to let imagination jade me.
                                                  --Shak.
      [1913 Webster]

   3. To exhaust by overdriving or long-continued labor of any
      kind; to tire, make dull, or wear out by severe or tedious
      tasks; to harass.
      [1913 Webster]

            The mind, once jaded by an attempt above its power,
            . . . checks at any vigorous undertaking ever after.
                                                  --Locke.

   Syn: To fatigue; tire; weary; harass.

   Usage: To Jade, Fatigue, Tire, Weary. Fatigue is the
          generic term; tire denotes fatigue which wastes the
          strength; weary implies that a person is worn out by
          exertion; jade refers to the weariness created by a
          long and steady repetition of the same act or effort.
          A little exertion will tire a child or a weak person;
          a severe or protracted task wearies equally the body
          and the mind; the most powerful horse becomes jaded on
          a long journey by a continual straining of the same
          muscles. Wearied with labor of body or mind; tired of
          work, tired out by importunities; jaded by incessant
          attention to business.
          [1913 Webster]

The Collaborative International Dictionary of English v.0.48:

jaded \jaded\ adj.
   1. dulled by surfeit; as, the amoral, jaded, bored upper
      classes.
      [WordNet 1.5]

   2. fatigued due to excess effort.

   Syn: wearied.
        [WordNet 1.5]

              my father's words had left me jaded and depressed
                                                  --William
                                                  Styron
        [WordNet 1.5]

WordNet (r) 3.0 (2006):

jaded
    adj 1: exhausted; "my father's words had left me jaded and
           depressed"- William Styron [syn: jaded, wearied]
    2: dulled by surfeit; "the amoral, jaded, bored upper classes"

Moby Thesaurus II by Grady Ward, 1.0:

136 Moby Thesaurus words for "jaded":
   allayed, apathetic, ausgespielt, benumbed, blase, bone-weary,
   bored, bushed, cloyed, crammed, dead, debilitated, disgusted,
   dispirited, dog-tired, done, done up, dopey, dormant, drooping,
   droopy, drugged, dull, effete, emptied, enervated, enfeebled,
   engorged, exanimate, exhausted, fagged, faint, fainting, far-gone,
   fatigued, fed up, fed-up, feeling faint, flagging, footsore,
   frazzled, full, full of, glutted, good and tired, gorged, heavy,
   hebetudinous, inanimate, inert, irked, lackadaisical, laid low,
   languid, languorous, leaden, lethargic, life-weary, lifeless,
   listless, lumpish, melancholic, melancholy, moribund, numb,
   overfed, overfull, overgorged, oversaturated, overstuffed,
   phlegmatic, played out, pooped, ready to drop, replete, run ragged,
   run-down, sagging, sated, satiate, satiated, satisfied, saturated,
   seedy, shotten, sick, sick of, slaked, sleepy, slow, sluggish,
   somnolent, spent, splenetic, stagnant, stagnating, stuffed,
   stultified, supersaturated, supine, surfeited, tired, tired of,
   tired of living, tired to death, tired-winged, toilworn, torpid,
   unrefreshed, unrestored, used up, vegetable, vegetative, wan,
   way-weary, wayworn, weak, weakened, weaned, wearied, weariful,
   weary, weary unto death, weary-footed, weary-laden, weary-winged,
   weary-worn, wilting, with a bellyful, with a snootful,
   with enough of, world-weary, worn, worn down, worn-down,
   worn-out