The Collaborative International Dictionary of English v.0.48:

Dispeople \Dis*peo"ple\, v. t. [imp. & p. p. Dispeopled; p.
   pr. & vb. n. Dispeopling.] [Pref. dis- + people: cf. F.
   d['e]peupler.]
   To deprive of inhabitants; to depopulate.
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         Leave the land dispeopled and desolate.  --Sir T. More.
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         A certain island long before dispeopled . . . by sea
         rivers.                                  --Milton.
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