The Collaborative International Dictionary of English v.0.48:

Blight \Blight\ (bl[imac]t), v. t. [imp. & p. p. Blighted; p.
   pr. & vb. n. Blighting.] [Perh. contr. from AS.
   bl[imac]cettan to glitter, fr. the same root as E. bleak. The
   meaning "to blight" comes in that case from to glitter,
   hence, to be white or pale, grow pale, make pale, bleach. Cf.
   Bleach, Bleak.]
   1. To affect with blight; to blast; to prevent the growth and
      fertility of.
      [1913 Webster]

            [This vapor] blasts vegetables, blights corn and
            fruit, and is sometimes injurious even to man.
                                                  --Woodward.
      [1913 Webster]

   2. Hence: To destroy the happiness of; to ruin; to mar
      essentially; to frustrate; as, to blight one's prospects.
      [1913 Webster]

            Seared in heart and lone and blighted. --Byron.
      [1913 Webster]

WordNet (r) 3.0 (2006):

blighted
    adj 1: affected by blight; anything that mars or prevents growth
           or prosperity; "a blighted rose"; "blighted urban
           districts" [syn: blighted, spoilt]

Moby Thesaurus II by Grady Ward, 1.0:

83 Moby Thesaurus words for "blighted":
   absolute, ausgespielt, baffled, balked, bankrupt, betrayed, bilked,
   blasted, blessed, blown, botched, broken, chapfallen, confounded,
   crestfallen, crossed, crushed, cursed, cussed, damnable, dashed,
   defeated, desolated, despoiled, destroyed, devastated,
   disappointed, dished, disillusioned, dissatisfied, done for,
   done in, down-and-out, downright, execrable, fallen, finished,
   flyblown, foiled, frowsty, frowsy, frowzy, frustrated, fusty,
   gone to pot, gross, ill done-by, ill-served, in ruins, infernal,
   irremediable, kaput, let down, maggoty, marred, mildewed,
   moldering, moldy, moth-eaten, musty, out of countenance,
   out-and-out, overthrown, rank, ravaged, regretful, ruined, ruinous,
   smutted, smutty, sorely disappointed, soured, spoiled, spoilt,
   straight-out, thwarted, undone, unmitigated, wasted, weevily,
   worm-eaten, wormy, wrecked