Wordnet 3.0
NOUN (1)
1. 
 a person who is destitute; 
- Example: "he tried to help the down-and-out"ADJECTIVE (1)
1. 
 lacking resources (or any prospect of resources); 
The Collaborative International Dictionary of English v.0.48:
down-and-out \down-and-out\ adj.
   1. impoverished; -- usually implying a state of dejection as
      well.
      [WordNet 1.5 +PJC]
   2. physically weak.
   Syn: down-and-out.
        [PJC]
The Collaborative International Dictionary of English v.0.48:
down-and-out \down-and-out\ n.
   a person who is destitute; as, he tried to help the
   down-and-out.
   [WordNet 1.5]
WordNet (r) 3.0 (2006):
down-and-out
    adj 1: lacking resources (or any prospect of resources)
    n 1: a person who is destitute; "he tried to help the down-and-
         out"
Moby Thesaurus II by Grady Ward, 1.0:
36 Moby Thesaurus words for "down-and-out":
   ausgespielt, bankrupt, blasted, blighted, broken, desolated,
   destitute, destroyed, devastated, done for, done in, fallen,
   finished, fortuneless, gone to pot, homeless, in ruins,
   in the gutter, in the red, insolvent, irremediable, kaput,
   landless, moneyless, out of funds, overthrown, penniless,
   propertyless, ravaged, ruined, ruinous, spoiled, undone, wasted,
   without a sou, wrecked