WordNet (r) 3.0 (2006):

nervous prostration
    n 1: an emotional disorder that leaves you exhausted and unable
         to work [syn: nervous exhaustion, nervous prostration]

Moby Thesaurus II by Grady Ward, 1.0:

19 Moby Thesaurus words for "nervous prostration":
   breakdown, circulatory collapse, collapse, crack-up, crackup,
   draining, exhaustedness, exhaustion, frayed nerves,
   frazzled nerves, jangled nerves, nervous breakdown,
   nervous exhaustion, neurasthenia, neurosis, prostration,
   raw nerves, shattered nerves, twanging nerves