1. an abnormal enlargement of the colon; can be congenital (as in Hirschsprung's disease) or acquired (as when children refuse to defecate);
WordNet (r) 3.0 (2006):
megacolon
n 1: an abnormal enlargement of the colon; can be congenital (as
in Hirschsprung's disease) or acquired (as when children
refuse to defecate)