The Collaborative International Dictionary of English v.0.48:
Signora \Si*gno"ra\, n. [It.] Madam; Mrs; -- a title of address or respect among the Italians. [1913 Webster]WordNet (r) 3.0 (2006):
signora n 1: an Italian title of address equivalent to Mrs. when used before a name 2: an Italian title or form of address for a married woman