The Collaborative International Dictionary of English v.0.48:

Holmes \Holmes\ n.
   Sherlock Holmes, a fictitious detective in novels by A. Conan
   Doyle.

   Syn: Sherlock Holmes.
        [WordNet 1.5]

WordNet (r) 3.0 (2006):

Holmes
    n 1: a fictitious detective in stories by A. Conan Doyle [syn:
         Sherlock Holmes, Holmes]
    2: United States jurist noted for his liberal opinions
       (1841-1935) [syn: Holmes, Oliver Wendell Holmes Jr.]
    3: United States writer of humorous essays (1809-1894) [syn:
       Holmes, Oliver Wendell Holmes]
    4: English geologist and supporter of the theory of continental
       drift (1890-1965) [syn: Holmes, Arthur Holmes]