Wordnet 3.0
NOUN (1)
1. 
 the brightest star in Virgo; 
The Collaborative International Dictionary of English v.0.48:
Spica \Spi"ca\, n.; pl. Spicae. [L., an ear, as of corn.]
   1. (Med.) A kind of bandage passing, by successive turns and
      crosses, from an extremity to the trunk; -- so called from
      its resemblance to a spike of a barley.
      [1913 Webster]
   2. (Astron.) A star of the first magnitude situated in the
      constellation Virgo.
      [1913 Webster] Spicate
WordNet (r) 3.0 (2006):
Spica
    n 1: the brightest star in Virgo