The Collaborative International Dictionary of English v.0.48:

Disease \Dis*ease"\, v. t. [imp. & p. p. Diseased; p. pr. &
   vb. n. Diseasing.]
   1. To deprive of ease; to disquiet; to trouble; to distress.
      [Obs.]
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            His double burden did him sore disease. --Spenser.
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   2. To derange the vital functions of; to afflict with disease
      or sickness; to disorder; -- used almost exclusively in
      the participle diseased.
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            He was diseased in body and mind.     --Macaulay.
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