The Collaborative International Dictionary of English v.0.48:

Destruction \De*struc"tion\, n. [L. destructio: cf. F.
   destruction. See Destroy.]
   1. The act of destroying; a tearing down; a bringing to
      naught; subversion; demolition; ruin; slaying;
      devastation.
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            The Jews smote all their enemies with the stroke of
            the sword, and slaughter, and destruction. --Esth.
                                                  ix. 5.
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            'Tis safer to be that which we destroy
            Than by destruction dwell in doubtful joy. --Shak.
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            Destruction of venerable establishment. --Hallam.
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   2. The state of being destroyed, demolished, ruined, slain,
      or devastated.
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            This town came to destruction.        --Chaucer.
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            Thou castedst them down into destruction. --Ps.
                                                  lxxiii. 18.
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   2. A destroying agency; a cause of ruin or of devastation; a
      destroyer.
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            The destruction that wasteth at noonday. --Ps. xci.
                                                  6.

   Syn: Demolition; subversion; overthrow; desolation;
        extirpation; extinction; devastation; downfall;
        extermination; havoc; ruin.
        [1913 Webster]

WordNet (r) 3.0 (2006):

destruction
    n 1: the termination of something by causing so much damage to
         it that it cannot be repaired or no longer exists [syn:
         destruction, devastation]
    2: an event (or the result of an event) that completely destroys
       something [syn: destruction, demolition, wipeout]
    3: a final state; "he came to a bad end"; "the so-called
       glorious experiment came to an inglorious end" [syn: end,
       destruction, death]