The Collaborative International Dictionary of English v.0.48:

Lame \Lame\ (l[=a]m), a. [Compar. Lamer (l[=a]m"[~e]r);
   superl. Lamest.] [OE. lame, AS. lama; akin to D. lam, G.
   lahm, OHG., Dan., & Sw. lam, Icel. lami, Russ. lomate to
   break, lomota rheumatism.]
   1.
      (a) Moving with pain or difficulty on account of injury,
          defect, or temporary obstruction of a function; as, a
          lame leg, arm, or muscle.
      (b) To some degree disabled by reason of the imperfect
          action of a limb; crippled; as, a lame man. "Lame of
          one leg." --Arbuthnot. "Lame in both his feet." --2
          Sam. ix. 13. "He fell, and became lame." --2 Sam. iv.
          4.
          [1913 Webster]

   2. Hence, hobbling; limping; inefficient; imperfect; as, a
      lame answer. "A lame endeavor." --Barrow.
      [1913 Webster]

            O, most lame and impotent conclusion! --Shak.
      [1913 Webster]

   Lame duck
      (a) (Stock Exchange), a person who can not fulfill his
          contracts. [Cant]
      (b) An elected politician who is completing a term after
          having been defeated at an election; also, an office
          holder who cannot or chooses not to run again for the
          same office; -- So called from the presumed lack of
          political power of one who is soon to be out of
          office.
      (b) Any office holder who is serving out a term after a
          replacement has been selected.
          [1913 Webster +PJC]

The Collaborative International Dictionary of English v.0.48:

Lame \Lame\ (l[=a]m), v. t. [imp. & p. p. Lamed (l[=a]md); p.
   pr. & vb. n. Laming.]
   To make lame.
   [1913 Webster]

         If you happen to let child fall and lame it. --Swift.
   [1913 Webster]

WordNet (r) 3.0 (2006):

lame
    adj 1: pathetically lacking in force or effectiveness; "a feeble
           excuse"; "a lame argument" [syn: feeble, lame]
    2: disabled in the feet or legs; "a crippled soldier"; "a game
       leg" [syn: crippled, halt, halting, lame, gimpy,
       game]
    n 1: someone who doesn't understand what is going on [syn:
         square, lame]
    2: a fabric interwoven with threads of metal; "she wore a gold
       lame dress"
    v 1: deprive of the use of a limb, especially a leg; "The
         accident has crippled her for life" [syn: cripple,
         lame]