The Collaborative International Dictionary of English v.0.48:

Rest \Rest\, n. [AS. rest, r[ae]st, rest; akin to D. rust, G.
   rast. OHG. rasta, Dan. & Sw. rast rest, repose, Icel. r["o]st
   the distance between two resting places, a mole, Goth. rasta
   a mile, also to Goth. razn house, Icel. rann, and perhaps to
   G. ruhe rest, repose, AS. r[=o]w, Gr. 'erwh`. Cf. Ransack.]
   1. A state of quiet or repose; a cessation from motion or
      labor; tranquillity; as, rest from mental exertion; rest
      of body or mind. --Chaucer.
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            Sleep give thee all his rest!         --Shak.
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   2. Hence, freedom from everything which wearies or disturbs;
      peace; security.
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            And the land had rest fourscore years. --Judges iii.
                                                  30.
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   3. Sleep; slumber; hence, poetically, death.
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            How sleep the brave who sink to rest,
            By all their country's wishes blest.  --Collins.
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   4. That on which anything rests or leans for support; as, a
      rest in a lathe, for supporting the cutting tool or
      steadying the work.
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            He made narrowed rests round about, that the beams
            should not be fastened in the walls of the house.
                                                  --1 Kings vi.
                                                  6.
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   5. (Anc. Armor) A projection from the right side of the
      cuirass, serving to support the lance.
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            Their visors closed, their lances in the rest.
                                                  --Dryden.
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   6. A place where one may rest, either temporarily, as in an
      inn, or permanently, as, in an abode. "Halfway houses and
      travelers' rests." --J. H. Newman.
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            In dust our final rest, and native home. --Milton.
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            Ye are not as yet come to the rest and to the
            inheritance which the Lord your God giveth you.
                                                  --Deut. xii.
                                                  9.
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   7. (Pros.) A short pause in reading verse; a caesura.
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   8. The striking of a balance at regular intervals in a
      running account. "An account is said to be taken with
      annual or semiannual rests." --Abbott.
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   9. A set or game at tennis. [Obs.]
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   10. (Mus.) Silence in music or in one of its parts; the name
       of the character that stands for such silence. They are
       named as notes are, whole, half, quarter,etc.
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   Rest house, an empty house for the accomodation of
      travelers; a caravansary. [India]

   To set one's rest or To set up one's rest, to have a
      settled determination; -- from an old game of cards, when
      one so expressed his intention to stand or rest upon his
      hand. [Obs.] --Shak. --Bacon.
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   Syn: Cessation; pause; intermission; stop; stay; repose;
        slumber; quiet; ease; quietness; stillness;
        tranquillity; peacefulness; peace.

   Usage: Rest, Repose. Rest is a ceasing from labor or
          exertion; repose is a mode of resting which gives
          relief and refreshment after toil and labor. The words
          are commonly interchangeable.
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WordNet (r) 3.0 (2006):

rest house
    n 1: a building used for shelter by travelers (especially in
         areas where there are no hotels)