The Collaborative International Dictionary of English v.0.48:

disoriented \disoriented\ adj.
   1. having lost one's bearings physically or mentally. I
      frequently find myself disoriented when I come up out of
      the subway;the anesthetic left her completely disoriented

   Syn: confused, lost.
        [WordNet 1.5]

   2. socially disoriented; withdrawn from social interactions.

   Syn: alienated, anomic.
        [WordNet 1.5 +PJC]

WordNet (r) 3.0 (2006):

disoriented
    adj 1: having lost your bearings; confused as to time or place
           or personal identity; "I frequently find myself
           disoriented when I come up out of the subway"; "the
           anesthetic left her completely disoriented" [syn:
           confused, disoriented, lost]
    2: socially disoriented; "anomic loners musing over their fate";
       "we live in an age of rootless alienated people" [syn:
       alienated, anomic, disoriented]