The Collaborative International Dictionary of English v.0.48:

Spice \Spice\, v. t. [imp. & p. p. Spiced; p. p. & vb. n.
   Spicing.]
   1. To season with spice, or as with spice; to mix aromatic or
      pungent substances with; to flavor; to season; as, to
      spice wine; to spice one's words with wit.
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            She 'll receive thee, but will spice thy bread
            With flowery poisons.                 --Chapman.
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   2. To fill or impregnate with the odor of spices.
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            In the spiced Indian air, by night.   --Shak.
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   3. To render nice or dainty; hence, to render scrupulous.
      [Obs.] "A spiced conscience." --Chaucer.
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The Collaborative International Dictionary of English v.0.48:

Spice \Spice\, n. [OE. spice, spece, spice, species, OF. espice,
   espece, F. ['e]pice spice, esp[`e]ce species, fr. L. species
   particular sort or kind, a species, a sight, appearance,
   show, LL., spices, drugs, etc., of the same sort, fr. L.
   specere to look. See Spy, and cf. Species.]
   1. Species; kind. [Obs.]
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            The spices of penance ben three.      --Chaucer.
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            Abstain you from all evil spice.      --Wyclif (1.
                                                  Thess,v. 22).
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            Justice, although it be but one entire virtue, yet
            is described in two kinds of spices. The one is
            named justice distributive, the other is called
            commutative.                          --Sir T.
                                                  Elyot.
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   2. A vegetable production of many kinds, fragrant or aromatic
      and pungent to the taste, as pepper, cinnamon, nutmeg,
      mace, allspice, ginger, cloves, etc., which are used in
      cookery and to flavor sauces, pickles, etc.
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            Hast thou aught in thy purse [bag] any hot spices?
                                                  --Piers
                                                  Plowman.
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   3. Figuratively, that which enriches or alters the quality of
      a thing in a small degree, as spice alters the taste of
      food; that which gives zest or pungency; a slight
      flavoring; a relish; hence, a small quantity or admixture;
      a sprinkling; as, a spice of mischief.
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            So much of the will, with a spice of the willful.
                                                  --Coleridge.
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WordNet (r) 3.0 (2006):

spice
    n 1: aromatic substances of vegetable origin used as a
         preservative
    2: any of a variety of pungent aromatic vegetable substances
       used for flavoring food
    3: the property of being seasoned with spice and so highly
       flavored [syn: spiciness, spice, spicery]
    v 1: make more interesting or flavorful; "Spice up the evening
         by inviting a belly dancer" [syn: spice, spice up]
    2: add herbs or spices to [syn: zest, spice, spice up]

Moby Thesaurus II by Grady Ward, 1.0:

183 Moby Thesaurus words for "spice":
   Tabasco, Worcestershire sauce, allspice, anchovies, angelica,
   applesauce, aroma, balm, balminess, basil, bell pepper, bite,
   black pepper, borage, bouquet, briskness, burnet, caper, capsicum,
   caraway seeds, cardamom, cast, catsup, celery salt, chervil, chili,
   chili sauce, chili vinegar, chives, chutney, cinnamon, cloves,
   color, condiment, condiments, coriander, cranberry sauce, cubeb,
   cumin, curry, dahl sauce, dash, dill, dillseed, duck sauce, elan,
   enliven, excitement, fagara, fennel, file, five spice powder,
   flavor, flavorer, flavoring, fragrance, fragrancy, fruitiness,
   garlic, garlic butter, garlic powder, garlic salt, ginger,
   green pepper, gusto, guts, hedge garlic, herb, hint, horseradish,
   hotness, hyssop, incense, infusion, inkling, inspirit, interest,
   intimation, invigorate, kick, leek, lick, life, liveliness, mace,
   marinade, marjoram, mayonnaise, mint, muskiness, mustard, nip,
   nippiness, nosegay, nutmeg, odor, onion, onion salt, oregano,
   paprika, parsley, pep, pepper, peppercorn, pepperiness, peppermint,
   perfume, piccalilli, pickle, pimento, pimpernel, piquancy,
   poignancy, potherb, punch, pungency, raciness, radish, red pepper,
   redolence, relish, saffron, sage, salad dressing, salt, sauce,
   sauce-alone, savor, savory, scent, season, seasoned salt, seasoner,
   seasoning, sesame oil, sesame seeds, shade, shallot, sharpness,
   smack, smell, snap, snappiness, soupcon, soy, soy sauce, spiciness,
   spirit, sprinkling, star anise, stimulant, stimulate, stimulation,
   suggestion, suspicion, sweet savor, sweet smell, taint, tang,
   tanginess, tarragon, tartar sauce, taste, tempering, thought,
   thyme, tinct, tincture, tinge, tint, tomato paste, touch, trace,
   turmeric, vanilla, vestige, vigor, vim, vinegar, white pepper,
   zest, zestfulness, zip



V.E.R.A. -- Virtual Entity of Relevant Acronyms (February 2016):

SPICE
       Scalable Parallel Intelligent Communications Engine


V.E.R.A. -- Virtual Entity of Relevant Acronyms (February 2016):

SPICE
       Simulation Program with Integrated Circuit Emphasis