Wordnet 3.0
NOUN (1)
1. 
 the private chapel of the popes in Rome; 
 it was built by and named after Sixtus IV in 1473; 
The Collaborative International Dictionary of English v.0.48:
Sistine \Sis"tine\, a.[It. sistino.]
   Of or pertaining to Pope Sixtus.
   [1913 Webster]
   Sistine chapel, a chapel in the Vatican at Rome, built by
      Pope Sixtus IV., and decorated with frescoes by Michael
      Angelo and others.
      [1913 Webster]
WordNet (r) 3.0 (2006):
Sistine Chapel
    n 1: the private chapel of the popes in Rome; it was built by
         and named after Sixtus IV in 1473