The Collaborative International Dictionary of English v.0.48:

Wrinkle \Wrin"kle\, v. t. [imp. & p. p. Wrinkled; p. pr. & vb.
   n. Wrinkling.]
   [1913 Webster]
   1. To contract into furrows and prominences; to make a
      wrinkle or wrinkles in; to corrugate; as, wrinkle the skin
      or the brow. "Sport that wrinkled Care derides." --Milton.
      [1913 Webster]

            Her wrinkled form in black and white arrayed.
                                                  --Pope.
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   2. Hence, to make rough or uneven in any way.
      [1913 Webster]

            A keen north wind that, blowing dry,
            Wrinkled the face of deluge, as decayed. --Milton.
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            Then danced we on the wrinkled sand.  --Bryant.
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   To wrinkle at, to sneer at. [Obs.] --Marston.
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The Collaborative International Dictionary of English v.0.48:

Wrinkle \Wrin"kle\, n.
   A winkle. [Local, U. S.]
   [1913 Webster]

The Collaborative International Dictionary of English v.0.48:

Wrinkle \Wrin"kle\, n. [OE. wrinkil, AS. wrincle; akin to OD.
   wrinckel, and prob. to Dan. rynke, Sw. rynka, Icel. hrukka,
   OHG. runza, G. runzel, L. ruga. ????.]
   [1913 Webster]
   1. A small ridge, prominence, or furrow formed by the
      shrinking or contraction of any smooth substance; a
      corrugation; a crease; a slight fold; as, wrinkle in the
      skin; a wrinkle in cloth. "The wrinkles in my brows."
      --Shak.
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            Within I do not find wrinkles and used heart, but
            unspent youth.                        --Emerson.
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   2. hence, any roughness; unevenness.
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            Not the least wrinkle to deform the sky. --Dryden.
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   3. [Perhaps a different word, and a dim. AS. wrenc a
      twisting, deceit. Cf. Wrench, n.] A notion or fancy; a
      whim; as, to have a new wrinkle. [Colloq.]
      [1913 Webster]

The Collaborative International Dictionary of English v.0.48:

Wrinkle \Wrin"kle\, v. i.
   To shrink into furrows and ridges.
   [1913 Webster]

WordNet (r) 3.0 (2006):

wrinkle
    n 1: a slight depression in the smoothness of a surface; "his
         face has many lines"; "ironing gets rid of most wrinkles"
         [syn: wrinkle, furrow, crease, crinkle, seam,
         line]
    2: a minor difficulty; "they finally have the wrinkles pretty
       well ironed out"
    3: a clever method of doing something (especially something new
       and different)
    v 1: gather or contract into wrinkles or folds; pucker; "purse
         ones's lips" [syn: purse, wrinkle]
    2: make wrinkles or creases on a smooth surface; make a pressed,
       folded or wrinkled line in; "The dress got wrinkled"; "crease
       the paper like this to make a crane" [syn: wrinkle,
       ruckle, crease, crinkle, scrunch, scrunch up,
       crisp]
    3: make wrinkled or creased; "furrow one's brow" [syn: furrow,
       wrinkle, crease]
    4: become wrinkled or crumpled or creased; "This fabric won't
       wrinkle" [syn: rumple, crumple, wrinkle, crease,
       crinkle]