The Collaborative International Dictionary of English v.0.48:

Trouble \Trou"ble\, v. t. [imp. & p. p. Troubled; p. pr. & vb.
   n. Troubling.] [F. troubler, OF. trobler, trubler,
   tourbler,fr. (assumed) LL. turbulare, L. turbare to
   disorderly group, a little crowd; both from turba a disorder,
   tumult, crowd; akin to Gr. ?, and perhaps to E. thorp; cf.
   Skr. tvar, tur,o hasten. Cf. Turbid.]
   1. To put into confused motion; to disturb; to agitate.
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            An angel went down at a certain season into the
            pool, and troubled the water.         --John v. 4.
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            God looking forth will trouble all his host.
                                                  --Milton.
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   2. To disturb; to perplex; to afflict; to distress; to
      grieve; to fret; to annoy; to vex.
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            Now is my soul troubled.              --John xii.
                                                  27.
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            Take the boy to you; he so troubles me
            'T is past enduring.                  --Shak.
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            Never trouble yourself about those faults which age
            will cure.                            --Locke.
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   3. To give occasion for labor to; -- used in polite
      phraseology; as, I will not trouble you to deliver the
      letter.
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   Syn: To disturb; perplex; afflict; distress; grieve; harass;
        annoy; tease; vex; molest.
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The Collaborative International Dictionary of English v.0.48:

Trouble \Trou"ble\, a.
   Troubled; dark; gloomy. [Obs.] "With full trouble cheer."
   --Chaucer.
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The Collaborative International Dictionary of English v.0.48:

Trouble \Trou"ble\, n. [F. trouble, OF. troble, truble. See
   Trouble, v. t.]
   1. The state of being troubled; disturbance; agitation;
      uneasiness; vexation; calamity.
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            Lest the fiend . . . some new trouble raise.
                                                  --Milton.
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            Foul whisperings are abroad; unnatural deeds
            Do breed unnatural troubles.          --Shak.
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   2. That which gives disturbance, annoyance, or vexation; that
      which afflicts.
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   3. (Mining) A fault or interruption in a stratum.
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   To get into trouble, to get into difficulty or danger.
      [Colloq.]

   To take the trouble, to be at the pains; to exert one's
      self; to give one's self inconvenience.
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            She never took the trouble to close them. --Bryant.
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   Syn: Affliction; disturbance; perplexity; annoyance;
        molestation; vexation; inconvenience; calamity;
        misfortune; adversity; embarrassment; anxiety; sorrow;
        misery.
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WordNet (r) 3.0 (2006):

trouble
    n 1: a source of difficulty; "one trouble after another delayed
         the job"; "what's the problem?" [syn: trouble, problem]
    2: an angry disturbance; "he didn't want to make a fuss"; "they
       had labor trouble"; "a spot of bother" [syn: fuss,
       trouble, bother, hassle]
    3: an event causing distress or pain; "what is the trouble?";
       "heart trouble"
    4: an effort that is inconvenient; "I went to a lot of trouble";
       "he won without any trouble"; "had difficulty walking";
       "finished the test only with great difficulty" [syn:
       trouble, difficulty]
    5: a strong feeling of anxiety; "his worry over the prospect of
       being fired"; "it is not work but worry that kills"; "he
       wanted to die and end his troubles" [syn: worry, trouble]
    6: an unwanted pregnancy; "he got several girls in trouble"
    v 1: move deeply; "This book upset me"; "A troubling thought"
         [syn: disturb, upset, trouble]
    2: to cause inconvenience or discomfort to; "Sorry to trouble
       you, but..." [syn: trouble, put out, inconvenience,
       disoblige, discommode, incommode, bother]
    3: disturb in mind or make uneasy or cause to be worried or
       alarmed; "She was rather perturbed by the news that her
       father was seriously ill" [syn: perturb, unhinge,
       disquiet, trouble, cark, distract, disorder]
    4: take the trouble to do something; concern oneself; "He did
       not trouble to call his mother on her birthday"; "Don't
       bother, please" [syn: trouble oneself, trouble, bother,
       inconvenience oneself]
    5: cause bodily suffering to and make sick or indisposed [syn:
       trouble, ail, pain]