The Collaborative International Dictionary of English v.0.48:

Afflict \Af*flict"\, p. p. & a. [L. afflictus, p. p.]
   Afflicted. [Obs.] --Becon.
   [1913 Webster]

The Collaborative International Dictionary of English v.0.48:

Afflict \Af*flict"\, v. t. [imp. & p. p. Afflicted; p. pr. &
   vb. n. Afflicting.] [L. afflictus, p. p. of affigere to
   cast down, deject; ad + fligere to strike: cf. OF. aflit,
   afflict, p. p. Cf. Flagellate.]
   1. To strike or cast down; to overthrow. [Obs.] "Reassembling
      our afflicted powers." --Milton.
      [1913 Webster]

   2. To inflict some great injury or hurt upon, causing
      continued pain or mental distress; to trouble grievously;
      to torment.
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            They did set over them taskmasters to afflict them
            with their burdens.                   --Exod. i. 11.
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            That which was the worst now least afflicts me.
                                                  --Milton.
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   3. To make low or humble. [Obs.] --Spenser.
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            Men are apt to prefer a prosperous error before an
            afflicted truth.                      --Jer. Taylor.
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   Syn: To trouble; grieve; pain; distress; harass; torment;
        wound; hurt.
        [1913 Webster]

WordNet (r) 3.0 (2006):

afflict
    v 1: cause great unhappiness for; distress; "she was afflicted
         by the death of her parents"
    2: cause physical pain or suffering in; "afflict with the
       plague" [syn: afflict, smite]