The Collaborative International Dictionary of English v.0.48:

Twinge \Twinge\ (tw[i^]nj), v. t. [imp. & p. p. Twinged
   (tw[i^]njd); p. pr. & vb. n. Twinging.] [OE. twengen, AS.
   twengan; akin to OE. twingen to pain, afflict, OFries.
   thwinga, twinga, dwinga, to constrain, D. dwingen, OS.
   thwingan, G. zwingen, OHG. dwingan, thwingan, to press,
   oppress, overcome, Icel. [thorn]vinga, Sw. tvinga to subdue,
   constrain, Dan. tvinge, and AS. [thorn]["u]n to press, OHG.
   d[=u]hen, and probably to E. thong. Perhaps influenced by
   twitch. Cf. Thong.]
   1. To pull with a twitch; to pinch; to tweak.
      [1913 Webster]

            When a man is past his sense,
            There's no way to reduce him thence,
            But twinging him by the ears or nose,
            Or laying on of heavy blows.          --Hudibras.
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   2. To affect with a sharp, sudden pain; to torment with
      pinching or sharp pains.
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            The gnat . . . twinged him [the lion] till he made
            him tear
            himself, and so mastered him.         --L'Estrange.
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The Collaborative International Dictionary of English v.0.48:

Twinge \Twinge\, v. i.
   To have a sudden, sharp, local pain, like a twitch; to suffer
   a keen, darting, or shooting pain; as, the side twinges.
   [1913 Webster]

The Collaborative International Dictionary of English v.0.48:

Twinge \Twinge\, n.
   1. A pinch; a tweak; a twitch.
      [1913 Webster]

            A master that gives you . . . twinges by the ears.
                                                  --L' Estrange.
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   2. A sudden sharp pain; a darting local pain of momentary
      continuance; as, a twinge in the arm or side. " A twinge
      for my own sin." --Dryden.
      [1913 Webster]

WordNet (r) 3.0 (2006):

twinge
    n 1: a sudden sharp feeling; "pangs of regret"; "she felt a stab
         of excitement"; "twinges of conscience" [syn: pang,
         stab, twinge]
    2: a sharp stab of pain
    v 1: cause a stinging pain; "The needle pricked his skin" [syn:
         prick, sting, twinge]
    2: feel a sudden sharp, local pain
    3: squeeze tightly between the fingers; "He pinched her behind";
       "She squeezed the bottle" [syn: pinch, squeeze, twinge,
       tweet, nip, twitch]