The Collaborative International Dictionary of English v.0.48:

Drug \Drug\ (dr[u^]g), v. i. [See 1st Drudge.]
   To drudge; to toil laboriously. [Obs.] "To drugge and draw."
   --Chaucer.
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The Collaborative International Dictionary of English v.0.48:

Drug \Drug\, n.
   A drudge (?). --Shak. (Timon iv. 3, 253).
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The Collaborative International Dictionary of English v.0.48:

Drug \Drug\, n. [F. drogue, prob. fr. D. droog; akin to E. dry;
   thus orig., dry substance, hers, plants, or wares. See
   Dry.]
   1. Any animal, vegetable, or mineral substance used in the
      composition of medicines.
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            Whence merchants bring
            Their spicy drugs. --Milton.
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   2. Any commodity that lies on hand, or is not salable; an
      article of slow sale, or in no demand; -- used often in
      the phrase "a drug on the market". "But sermons are mere
      drugs." --Fielding.
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            And virtue shall a drug become.       --Dryden.
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   3. any stuff used in dyeing or in chemical operations.
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   4. any substance intended for use in the treatment,
      prevention, diagnosis, or cure of disease, especially one
      listed in the official pharmacopoeia published by a
      national authority.
      [PJC]

   5. any substance having psychological effects, such as a
      narcotic, stimulant, or hallucinogenic agent, especially
      habit-forming and addictive substances, sold or used
      illegally; as, a drug habit; a drug treatment program; a
      teenager into drugs; a drug bust; addicted to drugs; high
      on drugs.

   Syn: illegal drug. [PJC]

              They [smaller and poorer nations] have lined up to
              recount how drug trafficking and consumption have
              corrupted their struggling economies and societies
              and why they are hard pressed to stop it. --
                                                  Christopher S.
                                                  Wren (N Y.
                                                  Times, June
                                                  10, 1998, p.
                                                  A5)
        [PJC]

The Collaborative International Dictionary of English v.0.48:

Drug \Drug\, v. i. [imp. & p. p. Drugged; p. pr. & vb. n.
   Drugging.] [Cf. F. droguer.]
   To prescribe or administer drugs or medicines. --B. Jonson.
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The Collaborative International Dictionary of English v.0.48:

Drug \Drug\, v. t.
   1. To affect or season with drugs or ingredients; esp., to
      stupefy by a narcotic drug. Also Fig.
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            The laboring masses . . . [were] drugged into
            brutish good humor by a vast system of public
            spectacles.                           --C. Kingsley.
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            Drug thy memories, lest thou learn it. --Tennyson.
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   2. To tincture with something offensive or injurious.
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            Drugged as oft,
            With hatefullest disrelish writhed their jaws.
                                                  --Milton.
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   3. To dose to excess with, or as with, drugs.
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            With pleasure drugged, he almost longed for woe.
                                                  --Byron.
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WordNet (r) 3.0 (2006):

drug
    n 1: a substance that is used as a medicine or narcotic
    v 1: administer a drug to; "They drugged the kidnapped tourist"
         [syn: drug, dose]
    2: use recreational drugs [syn: drug, do drugs]