The Collaborative International Dictionary of English v.0.48:

Destitute \Des"ti*tute\, a. [L. destitutus, p. p. of destituere
   to set away, leave alone, forsake; de + statuere to set. See
   Statute.]
   1. Forsaken; not having in possession (something necessary,
      or desirable); deficient; lacking; devoid; -- often
      followed by of.
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            In thee is my trust; leave not my soul destitute.
                                                  --Ps. cxli. 8.
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            Totally destitute of all shadow of influence.
                                                  --Burke.
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   2. Not possessing the necessaries of life; in a condition of
      want; needy; without possessions or resources; very poor.
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            They wandered about in sheepskins and goatskins;
            being destitute, afflicted, tormented. --Heb. xi.
                                                  37.
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The Collaborative International Dictionary of English v.0.48:

Destitute \Des"ti*tute\, v. t.
   1. To leave destitute; to forsake; to abandon. [Obs.]
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            To forsake or destitute a plantation. --Bacon.
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   2. To make destitute; to cause to be in want; to deprive; --
      followed by of. [Obs.]
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            Destituted of all honor and livings.  --Holinshed.
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   3. To disappoint. [Obs.]
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            When his expectation is destituted.   --Fotherby.
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WordNet (r) 3.0 (2006):

destitute
    adj 1: poor enough to need help from others [syn: destitute,
           impoverished, indigent, necessitous, needy,
           poverty-stricken]
    2: completely wanting or lacking; "writing barren of insight";
       "young recruits destitute of experience"; "innocent of
       literary merit"; "the sentence was devoid of meaning" [syn:
       barren, destitute, devoid, free, innocent]