WordNet (r) 3.0 (2006):

dysostosis multiplex
    n 1: hereditary disease (autosomal recessive) consisting of an
         error is mucopolysaccharide metabolism; characterized by
         severe abnormalities in development of skeletal cartilage
         and bone and mental retardation [syn: Hurler's syndrome,
         Hurler's disease, gargoylism, dysostosis multiplex,
         lipochondrodystrophy]