The Collaborative International Dictionary of English v.0.48:

Wholesome \Whole"some\, a. [Compar. Wholesomer; superl.
   Wholesomest.] [Whole + some; cf. Icel. heilsamr, G.
   heilsam, D. heilzaam.]
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   1. Tending to promote health; favoring health; salubrious;
      salutary.
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            Wholesome thirst and appetite.        --Milton.
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            From which the industrious poor derive an agreeable
            and wholesome variety of food.        --A Smith.
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   2. Contributing to the health of the mind; favorable to
      morals, religion, or prosperity; conducive to good;
      salutary; sound; as, wholesome advice; wholesome
      doctrines; wholesome truths; wholesome laws.
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            A wholesome tongue is a tree of life. --Prov. xv. 4.
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            I can not . . . make you a wholesome answer; my
            wit's diseased.                       --Shak.
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            A wholesome suspicion began to be entertained. --Sir
                                                  W. Scott.
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   3. Sound; healthy. [Obs.] --Shak.
      [1913 Webster] -- Whole"some*ly, adv. --
      Whole"some*ness, n.
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WordNet (r) 3.0 (2006):

wholesomeness
    n 1: the quality of being beneficial and generally good for you
         [ant: morbidity, morbidness, unwholesomeness]