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The Collaborative International Dictionary of English v.0.48:

Disnatured \Dis*na"tured\ (?; 135), a. [Pref. dis- + nature: cf.
   OF. desnatur['e], F. d['e]natur['e].]
   Deprived or destitute of natural feelings; unnatural. [Obs.]
   --Shak.
   [1913 Webster]