The Collaborative International Dictionary of English v.0.48:

Twinge \Twinge\ (tw[i^]nj), v. t. [imp. & p. p. Twinged
   (tw[i^]njd); p. pr. & vb. n. Twinging.] [OE. twengen, AS.
   twengan; akin to OE. twingen to pain, afflict, OFries.
   thwinga, twinga, dwinga, to constrain, D. dwingen, OS.
   thwingan, G. zwingen, OHG. dwingan, thwingan, to press,
   oppress, overcome, Icel. [thorn]vinga, Sw. tvinga to subdue,
   constrain, Dan. tvinge, and AS. [thorn]["u]n to press, OHG.
   d[=u]hen, and probably to E. thong. Perhaps influenced by
   twitch. Cf. Thong.]
   1. To pull with a twitch; to pinch; to tweak.
      [1913 Webster]

            When a man is past his sense,
            There's no way to reduce him thence,
            But twinging him by the ears or nose,
            Or laying on of heavy blows.          --Hudibras.
      [1913 Webster]

   2. To affect with a sharp, sudden pain; to torment with
      pinching or sharp pains.
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            The gnat . . . twinged him [the lion] till he made
            him tear
            himself, and so mastered him.         --L'Estrange.
      [1913 Webster]

The Collaborative International Dictionary of English v.0.48:

Twinge \Twinge\, v. i.
   To have a sudden, sharp, local pain, like a twitch; to suffer
   a keen, darting, or shooting pain; as, the side twinges.
   [1913 Webster]

The Collaborative International Dictionary of English v.0.48:

Twinge \Twinge\, n.
   1. A pinch; a tweak; a twitch.
      [1913 Webster]

            A master that gives you . . . twinges by the ears.
                                                  --L' Estrange.
      [1913 Webster]

   2. A sudden sharp pain; a darting local pain of momentary
      continuance; as, a twinge in the arm or side. " A twinge
      for my own sin." --Dryden.
      [1913 Webster]

WordNet (r) 3.0 (2006):

twinge
    n 1: a sudden sharp feeling; "pangs of regret"; "she felt a stab
         of excitement"; "twinges of conscience" [syn: pang,
         stab, twinge]
    2: a sharp stab of pain
    v 1: cause a stinging pain; "The needle pricked his skin" [syn:
         prick, sting, twinge]
    2: feel a sudden sharp, local pain
    3: squeeze tightly between the fingers; "He pinched her behind";
       "She squeezed the bottle" [syn: pinch, squeeze, twinge,
       tweet, nip, twitch]

Moby Thesaurus II by Grady Ward, 1.0:

58 Moby Thesaurus words for "twinge":
   ache, acute pain, agonize, ail, anguish, bite, blanch, blench,
   boring pain, charley horse, cramp, cramps, crick, darting pain,
   feel pain, feel the pangs, fulgurant pain, girdle pain, gnawing,
   grimace, gripe, griping, have a misery, hitch, hurt, jumping pain,
   kink, lancinating pain, misery, nip, pain, pang, paroxysm, pinch,
   pound, prick, seizure, sharp pain, shoot, shooting, shooting pain,
   shrink, smart, spasm, stab, stabbing pain, stitch, suffer, thrill,
   throb, throes, tingle, tormen, tweak, twitch, wince, wrench,
   writhe