The Collaborative International Dictionary of English v.0.48:

Irrespective \Ir`re*spec"tive\ ([i^]r`r[-e]*sp[e^]k"t[i^]v), a.
   1. Without regard for conditions, circumstances, or
      consequences; unbiased; independent; impartial; as, an
      irrespective judgment.
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            According to this doctrine, it must be resolved
            wholly into the absolute, irrespective will of God.
                                                  --Rogers.
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   2. Disrespectful. [Obs.] --Sir C. Cornwallis.
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   Irrespective of, regardless of; without regard to; as,
      irrespective of differences.
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