The Collaborative International Dictionary of English v.0.48:

Despite \De*spite"\, n. [OF. despit, F. d['e]pit, fr. L.
   despectus contempt, fr. despicere. See Despise, and cf.
   Spite, Despect.]
   1. Malice; malignity; spite; malicious anger; contemptuous
      hate.
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            With all thy despite against the land of Israel.
                                                  --Ezek. xxv.
                                                  6.
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   2. An act of malice, hatred, or defiance; contemptuous
      defiance; a deed of contempt.
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            A despite done against the Most High. --Milton.
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   In despite, in defiance of another's power or inclination.


   In despite of, in defiance of; in spite of. See under
      Spite. "Seized my hand in despite of my efforts to the
      contrary." --W. Irving.

   In your despite, in defiance or contempt of you; in spite
      of you. [Obs.]
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