The Collaborative International Dictionary of English v.0.48:

Handiwork \Hand"i*work`\ (-[i^]*w[^u]rk`), n. [OE. handiwerc,
   AS. handgeweorc; hand hand + geweorc work; prefix ge- +
   weorc. See Work.]
   Work done by the hands; hence, any work done personally.
   [1913 Webster]

         The firmament showeth his handiwork.     --Ps. xix. 1.
   [1913 Webster]

WordNet (r) 3.0 (2006):

handiwork
    n 1: a work produced by hand labor [syn: handicraft,
         handcraft, handiwork, handwork]

Moby Thesaurus II by Grady Ward, 1.0:

137 Moby Thesaurus words for "handiwork":
   accomplished fact, accomplishment, achievement, act, acta, action,
   adventure, architecture, artifact, assembly, blow, brainchild,
   building, casting, child, coinage, composition, concoction,
   construction, conversion, coup, crafting, craftsmanship, creation,
   creature, crowning achievement, cultivation, dealings, deed,
   devising, dirty work, distillation, doing, doings, donkeywork,
   drudgery, effect, effort, elaboration, employment, end product,
   endeavor, enterprise, erection, essence, exploit, extract,
   extraction, fabrication, fag, fait accompli, fashioning, fatigue,
   feat, formation, forming, formulation, framing, fruit, gest, go,
   grind, growing, hand, handicraft, handwork, harvesting, industry,
   invention, issue, job, labor, lick, lick of work, machining,
   making, maneuver, manual labor, manufacture, manufacturing,
   masterpiece, masterwork, measure, milling, mining, mintage, moil,
   molding, move, new mintage, offspring, opera, operation, opus,
   opuscule, origination, outcome, outgrowth, overt act, passage,
   performance, prefabrication, preparation, proceeding, processing,
   producing, product, production, raising, rat race, refining,
   res gestae, result, scut work, shaping, slavery, smelting,
   spadework, step, stroke, stroke of work, stunt, sweat, task, thing,
   thing done, tiresome work, toil, tour de force, transaction,
   travail, treadmill, turn, undertaking, work, workmanship, works