The Collaborative International Dictionary of English v.0.48:

Besot \Be*sot"\, v. t. [imp. & p. p. Besotted; p. pr. & vb. n.
   Besotting.]
   To make sottish; to make dull or stupid; to stupefy; to
   infatuate.
   [1913 Webster]

         Fools besotted with their crimes.        --Hudibras.
   [1913 Webster]

Moby Thesaurus II by Grady Ward, 1.0:

33 Moby Thesaurus words for "besot":
   KO, addle, anesthetize, bedaze, befuddle, bemuse, benumb, blunt,
   chloroform, coldcock, deaden, desensitize, dope, drug, dull,
   etherize, freeze, inebriate, intoxicate, kayo, knock out,
   knock senseless, knock stiff, knock unconscious, lay out,
   narcotize, numb, obtund, palsy, paralyze, put to sleep, stun,
   stupefy